Results 31 to 40 of about 2,783,970 (303)
The relationship between ideas about cleanliness and actions that affect product longevity [PDF]
As Mary Douglas famously put it, ‘where there is dirt there is system’ (1991 (1966): 35). She was concerned particularly with the cultural systems that determine the ideas about dirt that motivate and constrain people’s actions with material objects ...
Salvia, G +4 more
core
Familial longevity is marked by lower diurnal salivary cortisol levels: the leiden longevity study [PDF]
Background Reported findings are inconsistent whether hypothalamic-pituitary-adrenal (HPA) signaling becomes hyperactive with increasing age, resulting in increasing levels of cortisol.
Westendorp, Rudi G J +63 more
core +1 more source
Stable behavioral inhibition and glucocorticoid production as predictors of longevity [PDF]
Several personality/temperament traits have been linked to health outcomes in humans and animals but underlying physiological mechanisms for these differential outcomes are minimally understood. In this paper, we compared the strength of a behavioral trait (behavioral inhibition) and an associated physiological trait (glucocorticoid production) in ...
Sonia A, Cavigelli +4 more
openaire +2 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The possible interference of resistant pest’s populations to insecticides in natural enemies in the action thas not been clarified yet. Thus, this study aimed to evaluate Trichogramma pretiosum Riley (Hymenoptera: Trichogrammatidae) performance on ...
M. G. Barbosa +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Should we Subsidize Longevity? [PDF]
This paper studies the design of the optimal non linear taxation in an economy where longevity varies across agents, and depends on three factors: longevity genes, health investment and farsightedness.
Marie-Louise Leroux +2 more
core +4 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The field of anti-aging research has made remarkable strides with the identification of geroprotectors—compounds capable of extending healthspan and lifespan in animal models—presenting promising implications for human longevity.
Wannita Klinngam +10 more
doaj +1 more source

