Results 51 to 60 of about 2,783,970 (303)

The impact of the Hsp67Bc gene product on Drosophila melanogaster longevity, fecundity, and acute heat stress tolerance

open access: yesВавиловский журнал генетики и селекции, 2022
Drosophila melanogaster Hsp67Bc is a heat- and cold-inducible small heat shock protein that participates in the prevention of aggregation of misfolded proteins and in macroautophagy regulation. Overexpression of the Hsp67Bc gene has been shown to enhance
D. Malkeyeva   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Single and cross-generation natural hedging of longevity and financial risk [PDF]

open access: yes, 2012
The paper provides natural hedging strategies among death benefits and annuities written on a single and on different generations. It obtains closed-form Delta and Gamma hedges, in the presence of both longevity and interest rate risk.
Regis, Luca   +5 more
core   +1 more source

Breaking the Mortality Curve: Investment-Driven Acceleration in Life Expectancy and Insurance Innovation

open access: yesRisks
Capital investment in longevity science—research targeting the biological processes of aging through interventions like cellular reprogramming, AI-driven drug discovery, and biological age monitoring—may create significant divergence between traditional ...
David M. Dror
doaj   +1 more source

Customer Satisfaction Index (CSI) To Quality Product of Maiwa Breeding Centre In Makassar City [PDF]

open access: yesJournal of Global Innovations in Agricultural Sciences
This study aims to analyze the impact of the Customer Satisfaction Index (CSI) on product quality at Maiwa Breeding Centre (MBC). Data was collected from 118 respondents in Makassar City.
Sri Wira Utami, St. Rohani
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Effects of Polymorphism of the Growth Hormone Receptor (GHR) Gene on the Longevity and Milk Performance of White-Backed Cattle

open access: yesAnimals
Longevity is a trait influenced by numerous factors, including environmental factors, animal health, and productivity, which translate into economic considerations. In addition to many others, genetic factors are also very important.
Karolina Kasprzak-Filipek   +3 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Estimation of economic values in three breeding perspectives for longevity and milk production traits in Holstein dairy cattle in Iran

open access: yesItalian Journal of Animal Science, 2010
The objectives of this study were to estimate economic values (EVs) for three production traits (milk, fat and protein yields) and longevity and to develop a national selection index.
Abdolahad Shadparvar   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy