Results 91 to 100 of about 4,695,521 (310)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Discussion on the Supervision Mode of Quality and Safety Risk of Consumer Products
In recent years, China, as the world’s largest consumer products manufacturing country, has more and more consumer quality and safety incidents. By analyzing and constructing the supervision mode of quality and safety risks of consumer products, this ...
Chen Wenjie +6 more
doaj +1 more source
Organic Food Quality: Can it exist without Measurement? [PDF]
- Consumers who purchase organic foods are motivated primarily by the health benefits. What assurances are there that defining organic products based on inputs, methods, and ingredients will meet or exceed consumer expectations if there are no re ...
Ismond, Alan
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Food is vital to the people, and safety comes first in food. Food safety is crucial to people's livelihood, economic development, and social stability. It represents people's aspiration for a better life and grabs great public attention. In recent years,
Chun YANG +3 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
AbstractManufacturing engineering considers accuracy to be the degree to which parameters of a finished product conform to the dimensions, shape, and other characteristics specified in a technical drawing. A designer determines the level of manufacturing accuracy and surface roughness based on requirements to ensure the functional purpose of a product.
Vitalii Ivanov +3 more
openaire +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Green design of circuit breaker electrical life to improve resource utilization
A qualified circuit breaker possesses an inherent electrical life upon leaving the factory. During its operational lifespan, this electrical life gradually diminishes due to various factors, including electrical and mechanical wear.
Jungang Zhou, Zhaoxia Shang
doaj +1 more source

