Results 161 to 170 of about 17,831,371 (352)

Effect of genotype on performance, vitamin and carotenoid deposition, oxidative stability, fatty acid profile and sensory characteristics in cockerels housed on litter and in mobile boxes on pasture

Italian Journal of Animal Science
The study evaluated the effect of housing system and genotype on performance and breast meat quality in 540 cockerels. Three genotypes of cockerels differing in growth intensity (slow-growing ISA Dual, medium-growing Hubbard JA757 and fast-growing Ross ...
Michaela Englmaierová, Miloš Skřivan, Tomáš Taubner, Věra Skřivanová   +3 more
doaj   +1 more source

Vertical Product Differentiation When Quality is Unobservable to Buyers [PDF]

We analyze vertical product differentiation in a model where a good’s quality is unobservable to buyers before purchase, a continuum of quality levels is technologically feasible, and minimum quality is supplied under competitive conditions.
Gerhard Orosel, Klaus G. Zauner
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

PENGARUH PERSEPSI HARGA, KUALITAS PRODUK, KUALITAS PELAYANAN, DAN PENGALAMAN TERHADAP KEPUTUSAN PEMBELIAN SEPEDA MOTOR BEKAS PADA SHOWROOM DIDO MOTOR DI BLITAR [PDF]

This research aims to examine the influence of Price Perception (X1), Product Quality (X2), Service Quality (X3), and Experience (X4) on Purchasing Decisions (Y) at Dido Motor in Blitar.
Waskito, Intan Callista Putri
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Benefits and limits of quality cost concept applied to software industry [PDF]

Quality Cost approach is important to be implemented for each product or project of any software company, wherever it’s possible, because it provides additional and more accurate information about costs, costs determined by level of product/project ...
Catalin Afrasinei-Zavoianu
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

PENGARUH CITRA MEREK DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN SEPEDA MOTOR (Studi Pada Konsumen Honda Beat di Kecamatan Sukun, Kota Malang) [PDF]

The Influence of Brand Image on Purchase Decision, the Influence of Product Quality on Purchase Decision, and the Dominant Influence between Brand Image and Product Quality on Purchase Decision. This research was conducted in the Sukun District of Malang
ROSYIDI, MOCHAMMAD IMAM
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source