Results 71 to 80 of about 585,719 (254)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Diversity and Spatial Productivity Growth
Abstract Various strands of literature analyse the role of product diversity in influencing long-run growth and development. First, product diversification is at the heart of modern economic development and innovation-based endogenous growth theories.
Basile R., Cicerone G.
openaire +3 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Agricultura Tropica et SubtropicaThe black scale, Parlatoria ziziphi (Lucas, 1853), is a significant citrus pest that weakens trees, reduces fruit quality, and significantly lowers production, thereby affecting profitability.
Mezerdi Farid, Gacem Kamila
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A diversificação produtiva adotada pelos produtores fa-miliares das unidades de produção do município de passo fundo ao longo do tempo – uma estratégia de sustentabilidade [PDF]
Revista IDEAS, 2013 The study intended to understand the factors that induced transformations in rural properties in the city of Passo Fundo. By proposing a model of analysis that gathered together the tools derived from theories of production systems, typologies of ...
Luiz Fernando Fritz Filho +2 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Genetic diversity and forest reproductive material - from seed source selection to planting
iForest - Biogeosciences and Forestry, 2016 How much of genetic diversity is desirable in mass production of forest reproductive material? How mass production of forest reproductive material reduces genetic diversity?
Ivetić V +4 more
doaj +1 more source