Results 81 to 90 of about 679,373 (303)
In sub-Saharan Africa (SSA), the (sub)genotypes A1, D3, and E of the hepatitis B virus (HBV) prevail. Individuals infected with subgenotype A1 have a 4.5-fold increased risk of HCC compared to those infected with other (sub)genotypes.
Kiyasha Padarath +4 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
HBeAg is a non-structural, secreted protein of hepatitis B virus (HBV). Its p25 precursor is post-translationally modified in the endoplasmic reticulum.
Kiyasha Padarath +4 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A diversificação produtiva adotada pelos produtores fa-miliares das unidades de produção do município de passo fundo ao longo do tempo – uma estratégia de sustentabilidade [PDF]
The study intended to understand the factors that induced transformations in rural properties in the city of Passo Fundo. By proposing a model of analysis that gathered together the tools derived from theories of production systems, typologies of ...
Luiz Fernando Fritz Filho +2 more
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The black scale, Parlatoria ziziphi (Lucas, 1853), is a significant citrus pest that weakens trees, reduces fruit quality, and significantly lowers production, thereby affecting profitability.
Mezerdi Farid, Gacem Kamila
doaj +1 more source
Understanding Diversity in Early Neolithic Pottery Production
By recovering and interpreting the hidden technological variability in the first pottery at Ilindentsi-Massovets, this paper reveals the innovative adaptations to local conditions that the adoption of pottery production, as a new technology, must have ...
Tanya Dzhanfezova +2 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source

