Results 81 to 90 of about 679,373 (303)

Comparative Proteomic Analysis of Huh7 Cells Transfected with Sub-Saharan African Hepatitis B Virus (Sub)genotypes Reveals Potential Oncogenic Factors

open access: yesViruses
In sub-Saharan Africa (SSA), the (sub)genotypes A1, D3, and E of the hepatitis B virus (HBV) prevail. Individuals infected with subgenotype A1 have a 4.5-fold increased risk of HCC compared to those infected with other (sub)genotypes.
Kiyasha Padarath   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Comparison of the Proteome of Huh7 Cells Transfected with Hepatitis B Virus Subgenotype A1, with or without G1862T

open access: yesCurrent Issues in Molecular Biology
HBeAg is a non-structural, secreted protein of hepatitis B virus (HBV). Its p25 precursor is post-translationally modified in the endoplasmic reticulum.
Kiyasha Padarath   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A diversificação produtiva adotada pelos produtores fa-miliares das unidades de produção do município de passo fundo ao longo do tempo – uma estratégia de sustentabilidade [PDF]

open access: yesRevista IDEAS, 2013
The study intended to understand the factors that induced transformations in rural properties in the city of Passo Fundo. By proposing a model of analysis that gathered together the tools derived from theories of production systems, typologies of ...
Luiz Fernando Fritz Filho   +2 more
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Influence of temperature on the population dynamics of Parlatoria ziziphi and potential for biological control by the parasitoids Aphytis and Encarsia in citrus orchards

open access: yesAgricultura Tropica et Subtropica
The black scale, Parlatoria ziziphi (Lucas, 1853), is a significant citrus pest that weakens trees, reduces fruit quality, and significantly lowers production, thereby affecting profitability.
Mezerdi Farid, Gacem Kamila
doaj   +1 more source

Understanding Diversity in Early Neolithic Pottery Production

open access: yesDocumenta Praehistorica, 2020
By recovering and interpreting the hidden technological variability in the first pottery at Ilindentsi-Massovets, this paper reveals the innovative adaptations to local conditions that the adoption of pottery production, as a new technology, must have ...
Tanya Dzhanfezova   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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