FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Linked Heavy Particle Model and Multiple Particle Production [PDF]
, 1964 Tetsuro Kobayashi +2 more
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Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Statistical Model for Strange Particle and Isobar Production in Proton-Antiproton Annihilation [PDF]
, 1962 J. S. Kovacs
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ECONOMETRIC-PROCESS MODELS FOR INTEGRATED ASSESSMENT OF AGRICULTURAL PRODUCTION SYSTEMS [PDF]
This paper develops the conceptual and empirical basis for a class of empirical economic production models that can be linked to site-specific bio-physical models for use in integrated assessment research.
Antle, John M., Capalbo, Susan M.
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
A NUMERICAL MODEL FOR THE ESTIMATION OF PHOTOSYNTHETIC PRODUCTION, INTEGRATED OVER TIME AND DEPTH, IN NATURAL WATERS1 [PDF]
, 1969 Everett Fee
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Availability, production and competition: A model
Mathematical Modelling, 1987 Assume that s elements compete for a single item over a sequence of time intervals, not necessary of equal length. Denote any of the time intervals by (a,b). The length of each time interval is controlled by the model. The model makes use of knowledge which is acquired by statistical/possibilistic analysis of data which were obtained generally before ...
openaire +3 more sources
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Dynamic Articulatory Model of Speech Production [PDF]
, 1966 William L. Henke
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