Results 131 to 140 of about 1,962,028 (312)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A REVIEW AND EVALUATION OF WEATHER-CROP YIELD MODELS
The purpose of this paper is the relatively limited one of reviewing the literature for models which develop specific relationships between climatic variables and crop yields.
Geigel, Joanne M., Sundquist, W. Burt
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
, 2010 [[abstract]]We study the deterministic time-varying demand lot-sizing problem in which learning and forgetting in setups and production are considered simultaneously. It is an extension of Chiu's work.
Chiu, H. N.; H. M. Chen ; L. C. Weng
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From a Theory of Production to Data-Based Business Models
, 2019 Part 4: Data-Driven Production ManagementInternational audienceProducing companies are challenged by competition in global markets, in which customers have in general a strong negotiation position.
Sauermann, Frederick Christian +14 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
In this article, a model was developed in which the quantity and timing of input and harvest decisions are endogenous. The endogenous timing model allows all of the information about input and harvest behavior to be utilized, and it provides a basis for ...
Capalbo, Susan M. +2 more
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463472The application of machine learning models in production systems is continuously growing. Hence, ensuring a reliable estimation of the model performance is crucial, as all following decisions regarding the deployment of the machine learning models ...
Conrad, Felix +4 more
core +1 more source
Technique for improving care integration models [PDF]
, 2011 Recent developments in technologies and improved life style have had a positive impact on prolonging human life contributing to the increasing elderly population. As a consequence, many countries (particularly developed ones) started to experience higher
Zulkepli, J, Eldabi, T
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source