Results 111 to 120 of about 495,373 (264)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A Note on Numerical Estimation of Sato’s Two-Level CES Production Function
In this paper Sato’s two-level CES production function has been estimated by nonlinear regression carried out through five different methods of optimization, namely, the Hooke-Jeeves Pattern Moves (HJPM), the Hooke-Jeeves-Quasi-Newton (HJQN), the ...
Mishra, SK
core
Decision support for build-to-order supply chain management through multiobjective optimization
, 2010 This paper aims to identify the gaps in decision-making support based on multiobjective optimization for build-to-order supply chain management (BTOSCM).
Gallear, D, Mansouri, A, Askariazad, M
core
Real-time Optimization and Control for Oil Production under Uncertainty [PDF]
The practical use of model-based optimization depends significantly on the accuracy of the model in use. This is because the presence of uncertainty can introduce a mismatch between the model and the real plant, which may eventually lead to suboptimal or
Janatian, Nima
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Optimization of carboxymetyhlcellulase and polyoses production from oil palm empty fruit bunch fermentation by Trichoderma Virens [PDF]
, 2012 Optimization of CMCase and polyoses production by Trichoderma virens via batch culture fermentation of pretreated oil palm empty fruit bunch (OPEFB) was carried out using statistical software of Design Expert ® version 6.0.4. The General Factorial Design
Mohd. Tumpang, Nurrazean Haireen
core
Revista Facultad Nacional de Agronomía Medellín, 2009 El cultivo de células vegetales ha surgido como una alternativa para la obtención de metabolitos de alto valor agregado, producidos en las plantas en bajas concentraciones y para los cuales, no existen procesos de síntesis química conocidos; sin embargo,
Mario Arias Zabala +4 more
doaj
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
An open source platform addressing structural stability risk assessment in historical centres
GromaThe management of stability risk assessment in historical centres in a project that aims to design and develop an open platform where blocks of buildings and large structures may be represented in damage maps before the event occurs, addressing damage ...
Renzo Carlucci +9 more
doaj +1 more source