Results 141 to 150 of about 495,373 (264)

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Production cost reduction through optimization of machine component

open access: yes, 2014
This thesis aiming to reduce the cost of production through analyzing and optimizing a set of weaving machine components including five legs; three main legs and two support legs.
Delavar, Reza, Rezazadeh, Mehdi
core  

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Robust Solutions of Optimization Problems Affected by Uncertain Probabilities

open access: yes
In this paper we focus on robust linear optimization problems with uncertainty regions defined by ø-divergences (for example, chi-squared, Hellinger, Kullback-Leibler).
De Waegenaere, A.M.B.   +4 more
core  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

AI-guided biorefinery optimization for the production of lignin-carbohydrate complexes with tailored properties

open access: yes
Lignin-carbohydrate complexes (LCCs) present a unique prospect for exploiting the synergy between lignin and carbohydrates in high-value products. To date, the production of LCCs in high yields is still an open challenge.
Daryna, Diment   +9 more
core   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Self-Optimization In Gear Manufacturing And Assembly For Automotive Electric Drive Production

open access: yes
538547Due to the trend of electrification in the automotive industry, the economic production of electric drives with high acoustic quality requirements is a crucial factor to stay competitive in the global market. Low noise levels in the interior are an
Friedrich, Bastian   +2 more
core   +1 more source

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