Results 171 to 180 of about 7,991,419 (293)

Script concordance tests production optimization using enhanced interactive training: randomized, single-blind, bicentric trial. [PDF]

BMC Med Educ
Gaillet A, Cottereau AS, Cariou A, Lebeaux D, Lemogne C, de Prost N, Vodovar D, Roux D.   +7 more
europepmc   +1 more source

Micrococcus lylae MW407006 Pigment: Production, Optimization, Nano-Pigment Synthesis, and Biological Activities. [PDF]

Biology (Basel), 2022
Shahin YH, Elwakil BH, Ghareeb DA, Olama ZA.   +3 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

A Bio-Inspired Comprehensive Learning Strategy-Enhanced Parrot Optimizer: Performance Evaluation and Application to Reservoir Production Optimization. [PDF]

Biomimetics (Basel)
Yu B, Zhang Y.
europepmc   +1 more source

Biotechnological production optimization of argyrins - a potent immunomodulatory natural product class. [PDF]

Microb Biotechnol, 2022
Pogorevc D, Müller R.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Pulsed Dynamic Water Electrolysis: Mass Transfer Enhancement, Microenvironment Regulation, and Hydrogen Production Optimization. [PDF]

Nanomicro Lett
Zhang X, Zhou W, Meng X, Huang Y, Yu Y, Zhao H, Wang L, Sun F, Gao J, Zhao G.   +9 more
europepmc   +1 more source

Production optimization in the time of pandemic: an SIS-based optimal control model with protection effort and cost minimization. [PDF]

Ann Oper Res, 2023
Brusset X, Jebali A, La Torre D, Liuzzi D.   +3 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Design and application of an efficient cellulose-degrading microbial consortium and carboxymethyl cellulase production optimization. [PDF]

Front Microbiol, 2022
Zhang G, Dong Y.
europepmc   +1 more source