Results 51 to 60 of about 19,558,547 (301)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Optimization of Streptomyces sp.A11 Medium Cultivation on Cyclo(Tyrosyl-Prolyl) Production Using The Response Surface Methodology [PDF]
The response surface methodology is a three factorial design which provides the relationship between one or more measured dependent response and a number of input (independent) factors.
Rofiq , Sunaryanto
core +1 more source
Strategies to Enhance Periplasmic Recombinant Protein Production Yields in Escherichia coli
Main reasons to produce recombinant proteins in the periplasm of E. coli rather than in its cytoplasm are to -i- enable disulfide bond formation, -ii- facilitate protein isolation, -iii- control the nature of the N-terminus of the mature protein, and -iv-
Alexandros Karyolaimos +1 more
doaj +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Informed production optimization in hydrocarbon reservoirs
The exploitation of subsurface hydrocarbon reservoirs is achieved through the control of production and injection wells (i.e., by prescribing time-varying pressures and flow rates) to create conditions that make the hydrocarbons trapped in the pores of ...
E. Barros, P. M. J. Hof, J. Jansen
semanticscholar +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Circular Economy (CE) has increasingly emerged as a viable economic model for organizations across the globe. Nevertheless, despite this heightened attention, there is still a lack of in-depth discussion on how circular products should be conceived ...
Paulo Henrique Paulista +3 more
doaj +1 more source
Applications of Machine Learning in Subsurface Reservoir Simulation—A Review—Part II
In recent years, Machine Learning (ML) has become a buzzword in the petroleum industry, with numerous applications which guide engineers in better decision making.
Anna Samnioti, Vassilis Gaganis
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

