Results 91 to 100 of about 4,356,275 (291)

Orbit transfer vehicle engine study. Volume 3: Program costs [PDF]

open access: yes
Budgetary and planning cost estimates are presented that were prepared for the development, production and operation and flight support phases for each of the engines proposed for OTV propulsion.

core   +1 more source

Smart Postharvest Management of Strawberries: YOLOv8-Driven Detection of Defects, Diseases, and Maturity

open access: yesAgriEngineering
Strawberries are highly perishable fruits prone to postharvest losses due to defects, diseases, and uneven ripening. This study proposes a deep learning-based approach for automated quality assessment using the YOLOv8n object detection model.
Luana dos Santos Cordeiro   +2 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Structuring Corporate Governance in the Context of Crisis: Lessons from the COVID-19 Pandemic in a Nonprofit Organization

open access: yesAdministrative Sciences
This study aimed to analyze the adaptations in the corporate governance practices of a Brazilian support foundation, in the context of the crisis caused by the COVID-19 pandemic.
Raffaella Regueira de Oliveira   +2 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Analysis, Design and Implementation of Biodiesel Projects in Brazil [PDF]

open access: yes
During the oil crisis of the seventies, Brazil has developed a successful program for gasoline substitution by ethanol (Proálcool). Nowadays the biomass accounts for 27% of total national energy consumed in Brazil and the ethanol participates with 40% of
da Silva Junior, Aziz Galvao   +2 more
core   +1 more source

Rubidium frequency standard test program for NAVSTAR GPS [PDF]

open access: yes, 1978
Test data of the RFS Program in the Production phase and computer automation are presented, as an essential element in the evaluation of the RFS performance in a simulated spacecraft environment.
Dederich, D. J., Koide, F.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Multi-attribute monitoring (MAM) methodology for glycosylated subunit vaccines

open access: yesScientific Reports
Many protein-based vaccines comprise viral surface proteins which are chosen for their ability to stimulate the immune system. These vaccine molecules are often heavily glycosylated, and glycosylation plays critical roles in the immunological and ...
Asif Shajahan   +17 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy