Results 141 to 150 of about 16,758,400 (349)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Analysis, Design and Implementation of Biodiesel Projects in Brazil [PDF]

open access: yes
During the oil crisis of the seventies, Brazil has developed a successful program for gasoline substitution by ethanol (Proálcool). Nowadays the biomass accounts for 27% of total national energy consumed in Brazil and the ethanol participates with 40% of
da Silva Junior, Aziz Galvao   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

AUTONOMOUS CT REPLACEMENT METHOD FOR THE SKULL PROSTHESIS MODELLING

open access: yesFacta Universitatis. Series: Mechanical Engineering, 2015
The geometric modeling of prosthesis is a complex task from medical and engineering viewpoint. A method based on CT replacement is proposed in order to circumvent the related problems with the missing information to modeling.
Marcelo Rudek   +2 more
doaj  

Improvement in stands pricing and candidate companies allocation at agricultural exposition

open access: yesJournal of the Saudi Society of Agricultural Sciences
Agricultural expositions are events aimed at product sales, training, technology dissemination, and integration between the agricultural sector and urban residents.
Ronier Gutierrez   +4 more
doaj   +1 more source

LEADING INDICATORS OF REGIONAL COTTON ACREAGE RESPONSE: STRUCTURAL AND TIME SERIES MODELING RESULTS [PDF]

open access: yes
Resurgent cotton production compels better acreage forecasts for planning seed, chemical, and other input requirements. Structural models describe leading acreage response indicators, and forecasts are compared to time-series models.
Houston, Jack E.   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Augmented Reality Applied to Identify Aromatic Herbs Using Mobile Devices

open access: yesAgriEngineering
Correctly identifying and classifying food is decisive in food safety. The food sector is constantly evolving, and one of the technologies that stands out is augmented reality (AR). During practical studies at Companhia de Entreposto e Armazéns Gerais de
William Aparecido Celestino Lopes   +6 more
doaj   +1 more source

Lunar Resource Assessment: an Industry Perspective [PDF]

open access: yes
The goals of the U.S. space program are to return to the Moon, establish a base, and continue onward to Mars. To accomplish this in a relatively short time frame and to avoid the high costs of transporting materials from the Earth, resources on the Moon ...
Altenberg, B. H.   +2 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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