Results 71 to 80 of about 16,758,400 (349)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

ESSENCE OF MANAGEMENT OF AN ENTERPRISE PRODUCTION PROGRAM AND THE ROLE OF ANALYSIS IN THIS PROCESS

Russian Journal of Economics and Law, 2012
The article presents critical investigation of the existing approaches to the production program management and proposes the author's interpretation of the mentioned category.
O. V. Askanova
doaj  

Correlation between sustainability and smartness indicators in Brazilian cities: insights from the 5SenSu model

Frontiers in Sustainable Cities
To face the growing challenges of urbanization, urban management models grounded in the principles of sustainability and smart cities are being proposed.
Pedro Pierucci, Feni Agostinho, Cecília M. V. B. Almeida, Fernando J. C. Demétrio, Biagio F. Giannetti   +4 more
doaj   +1 more source

Monte-Carlo simulations of photohadronic processes in astrophysics [PDF]

, 1999
A new Monte Carlo program for photohadronic interactions of relativistic nucleons with an ambient photon radiation field is presented. The event generator is designed to fulfil typical astrophysical requirements, but can also be used for radiation and ...
Engel, Ralph, Muecke, A., Protheroe, R. J., Rachen, J. P., Stanev, Todor   +4 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sheep production: Program recommended

California Agriculture, 1948
Sheep form an important part of California agriculture. Thousands of acres of the state's grazing land can be utilized best by sheep. Since sheep fit well into grain farming rotation to restore soil fertility, they can be used profitably on the worn out ...
R Miller
doaj  

Rubidium frequency standard test program for NAVSTAR GPS [PDF]

, 1978
Test data of the RFS Program in the Production phase and computer automation are presented, as an essential element in the evaluation of the RFS performance in a simulated spacecraft environment.
Dederich, D. J., Koide, F.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Edge AI for Industrial Visual Inspection: YOLOv8-Based Visual Conformity Detection Using Raspberry Pi

Algorithms
This paper presents a lightweight and cost-effective computer vision solution for automated industrial inspection using You Only Look Once (YOLO) v8 models deployed on embedded systems.
Marcelo T. Okano, William Aparecido Celestino Lopes, Sergio Miele Ruggero, Oduvaldo Vendrametto, João Carlos Lopes Fernandes   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source