Results 81 to 90 of about 4,154,339 (340)

Top-quark production at the LHC: differential cross section and phenomenological applications

, 2013
We discuss top-quark pair production at hadron colliders and review available calculations of differential top-pair production cross section in perturbative QCD at approximate next-to-next-to-leading order (NNLO) within the threshold resummation ...
Guzzi, Marco, Lipka, Katerina, Moch, Sven-Olaf   +2 more
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Organic Hop Variety Trial: Results from Year Five [PDF]

, 2015
Hops production continues to increase throughout the the Northeast. While hops were historically grown in the Northeast, they have not been commercially produced in this region for over a hundred years.
Calderwood, Lily, Cubins, Julija, Cummings, Erica, Darby, Heather, Gupta, Abha, Lewins, Scott, Post, Julian Post, Ziegler, Sara   +7 more
core   +1 more source

On Cascade Products of Answer Set Programs [PDF]

Theory and Practice of Logic Programming, 2014
AbstractDescribing complex objects by elementary ones is a common strategy in mathematics and science in general. In their seminal 1965 paper, Kenneth Krohn and John Rhodes showed that every finite deterministic automaton can be represented (or “emulated”) by a cascade product of very simple automata. This led to an elegant algebraic theory of automata
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Carbon Footprint of Electricity Generation in Brazil: An Analysis of the 2016–2026 Period

Energies, 2018
The present paper aims to evaluate the past and future environmental performance of the electricity generation in Brazil in terms of Global Warming Potential (GWP) and Global Temperature Potential (GTP).
Murillo Vetroni Barros, Cassiano Moro Piekarski, Antonio Carlos de Francisco   +2 more
doaj   +1 more source

A Proposed Livestock Research Program for Alaska [PDF]

, 1963
This report presents, primarily, areas of research and research goals on range management and beef cattle production that 1) appear to be most urgent and 2) that appear attainable within the next few years without a great expansion of personnel ...
Story, Charles D.
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source