Results 41 to 50 of about 285,950 (266)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Effect of sex-linked dwarf gene on exterior appearance, productive performance and egg characteristics in a colored broiler dam line [PDF]

open access: yesBiotechnology in Animal Husbandry, 2015
The effect of sex-linked dwarf gene was investigated through comparison of dwarf hens with their full-sib normal sisters obtained by mating heterozygous males (DW/dw) to normal females (DW/_) from line F (used as maternal form for production of slow ...
Mincheva N.   +4 more
doaj  

Estimation of Genetic Parameters for Conformation Traits and Milk Production Traits in Chinese Holsteins

open access: yesAnimals, 2022
The objective of this study was to explore the genetic parameters of conformation traits and milk production traits in Chinese Holstein cattle and to provide a reference for dairy cattle breeding. We collected the phenotypic data of 23 conformation traits and five milk production traits of Chinese Holsteins and used animal models to estimate the ...
Xue, Xiaoshu   +7 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Genetic Diversity and Differentiation of Silkworm (Bombyx mori) Local Germplasm Resources in China and Uzbekistan

open access: yesInsects
Silkworm (Bombyx mori) is an economically significant insect that produces silk and makes important contributions to the development of silk-producing countries.
Xia Xu   +11 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

ПРОУЧВАНЕ НА ИЗМЕНЕНИЕТО НА ПРОДУКТИВНИТЕ ПРИЗНАЦИ МЛЕЧНОСТ И ПЛОДОВИТОСТ ПРИ ОВЦЕ ОТ СИНТЕТИЧНА ПОПУЛАЦИЯ БЪЛГАРСКА МЛЕЧНА В РЕЗУЛТАТ НА ПРОВЕЖДАНАТА СЕЛЕКЦИЯ

open access: yesЖивотновъдни науки, 2015
Analyzing the level of productivity in individual herds and the entire dairy crossbred population significantly affect the right direction of breeding process, aimed at improving its valuable productive and quality traits.
ПЕТЯ Славова   +2 more
doaj  

Synbiotics as functional additives in broiler diets: Production and slaughter performance [PDF]

open access: yesActa Agriculturae Serbica
To enhance the safety and efficiency of broiler nutrition, this study investigated the effects of a synbiotic product containing both probiotic and prebiotic components, administered through drinking water.
Petričević Veselin   +6 more
doaj   +1 more source

Polymorphism of bovine STAT5A gene and its association with milk production traits in crossbred cattle of Kerala, India

open access: yesIndian Journal of Animal Sciences, 2022
Signal transducer and activator of transcription 5A (STAT5A) is a transcription factor that mediates signals from prolactin and growth hormone, the corresponding main regulators of lactation and growth of mammals.
Jamuna Valsalan   +3 more
doaj   +1 more source

Immunocompetence traits and their association with production traits in CARI-Debendra chicken

open access: yesThe Indian Journal of Animal Sciences, 2014
The immunocompetence (IC) status of any animal breed indicates about its general response to diseases. Single hatched CARI-Debendra (CD) chicks (84) were evaluated for IC traits (in vivo antibody response to SRBC, serum lysozyme and serum IgG concentrations) and their association with production traits in layer. According to least square mean analysis,
ANANTA KUMAR DAS   +4 more
openaire   +1 more source

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