Impact of stocking density on beef heifer productive performance and health through hematology and <i>longissimus dorsi</i> ultrasound. [PDF]
Front Vet SciLisuzzo A +10 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Dietary Supplementation with <i>Zanthoxylum bungeanum</i> Seed Cake and Meal Improves the Productive Performance and Antioxidant Capacity of Laying Hens. [PDF]
Animals (Basel)Cao S, Lin H, Li X, Li X, Zhao J, Liu J.
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Characterizing the Optimal Composition of Government Expenditures [PDF]
This paper extends the neoclassical growth model with productive public capital by including an infrastructure efficiency index, which is assumed to depend on a public choice variable, in particular, the share of public spending allocated to productive ...
Rafaela Pérez Sánchez
core
Effects of Amino Acid Supplementation in Low-Protein Diets on Productive Performance, Digestive Function, and Intestinal Health of Laying Hens. [PDF]
Animals (Basel)Zhang C +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Financial exposure and productive performance in French arable farms
, 2006 International audienceThis paper examines the dynamic relationship between financial exposure and productive performance in agriculture. To this end, Granger’s concept of causality and VAR representation are used. Indeed, in spite of several studies, the
Blancard, Stéphane
core
Cooperative management practices how to influence the productive performance outcomes: Based on the analysis of China's guangxi 94 farmers professional cooperatives. [PDF]
PLoS OneZhao YD +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source