Results 221 to 230 of about 8,931,346 (309)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Effect of feeding mulberry leaves on nutrient digestibility, carcass characteristics, blood parameters and productive performance of growing Flanders rabbits. [PDF]

Trop Anim Health Prod
Hassanien HAM, Elkassas NM, Mohamed RA, El-Bltagy E, Fayad S, El Naggar S, Salem AZM.   +6 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effects of ACOT7 gene variants on productive performance in Qiandongnan small Xiang goats. [PDF]

Sci Rep
Liu H, Chen X, Zhou B, Li Z, Zhou B, An D, Xu J, Ruan Y.   +7 more
europepmc   +1 more source

Modernising the NHS: Performance and productivity

BMJ, 2000
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Productive Performance and Egg Quality Traits of Exotic Chicken Breeds Reared Under Traditional Management System in Misrak Silte District, Central Ethiopia. [PDF]

Scientifica (Cairo)
Sirmolo M, Asresie A, Salo S, Tadele Y.
europepmc   +1 more source

Performing Production

openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Effects of Dietary Thymus vulgaris on Laying Hens: A Systematic Review and Meta-Analysis of Productive Performance and Egg Quality. [PDF]

Vet Med Sci
Hassanpour H, Nasiri L, Fallah AA, Karimi-Shayan T.   +3 more
europepmc   +1 more source