Results 121 to 130 of about 4,239,244 (275)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan   +9 more
wiley   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

open access: yesAdvanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti   +6 more
wiley   +1 more source

Heat transfer analysis of premixed low calorific value landfill gas impinging flame under oxygen and hydrogen enrichment

open access: yesResults in Engineering
The effective utilization of low-calorific value gases is important for meeting growing demand of energy and also addressing associated environmental concerns. In this study, the heat transfer of impinging flames of low-calorific value landfill gas (BG30)
Kangdong Chen   +3 more
doaj   +1 more source

Active Facilitation: What Do Specialists Need to Know and How Might They Learn It? [PDF]

open access: yes, 2005
Sustained, innovative professional development is now widely acknowledged as essential to the improvement of mathematics instruction in the nation’s schools. In recent years, this recognition has prompted the production of a variety of materials designed
Lester, J. B., Schifter, D.
core   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Exploring the role of internal social media in fostering employee green behavior (EGB)

open access: yesSustainable Futures
Previous research has consistently highlighted the impact of internal communication strategies on employees’ pro-environmental behavior. However, the effect of internal social media on employee green behavior (EGB) and its underlying relationships ...
Peggy M.L. Ng   +6 more
doaj   +1 more source

Entry-Level Competencies of New Student Affairs Professionals: A Delphi Study [PDF]

open access: yes, 2005
The study examines the perceptions of 104 mid- and senior-level student affairs administrators of positions, responsibilities, competencies, and theories important for professional practice for new student affairs professionals. In regard to competencies,
Burkard, Alan W.   +3 more
core   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

The potential of mobile phones to transform teacher professional development [PDF]

open access: yes, 2014
Futures thinking is used by governments to consider long-term strategic approaches and develop policies and practices that are potentially resilient to future uncertainty.
Shrestha, Prithvi   +3 more
core  

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