Results 51 to 60 of about 1,077,176 (268)
Professor Fernando Costa— A Man Ahead of His Time
Brazilian Neurosurgery, 2019 This article describes the milestones in the life Brazil’s greatest neurosurgeons, Professor Fernando Costa. Born and raised in the city of Pelotas, RS, Professor Fernando was an exemplary doctor.
Gustavo Rassier Isolan
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
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Parâmetros Curriculares Nacionais de Matemática (1990): pareceres sobre o ensino de frações
Revista Venezolana de Investigación en Educación Matemática, 2022 Este artigo refere-se aos Parâmetros Curriculares Nacionais –PCN– e os debates que essa referência curricular brasileira dos anos de 1990 ensejaram sobre o ensino de frações. Deseja-se saber: O que educadores matemáticos nas suas discussões e análises da
Diego Rodrigues da Silva +1 more
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This statement is a protest against irrelevant citation of psychological research for justification of unreasonable discrimination. Brief English version is in OSF supplemental materials (https://osf.io/e5yt4/). Please feel free to share!
Asako Miura +4 more
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
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COMO SE CONSTITUI A ATIVIDADE DOCENTE? UMA ANÁLISE PELA PSICOLOGIA HISTÓRICO-CULTURAL [PDF]
Psicologia Escolar e EducacionalRESUMO A Teoria da Atividade desenvolvida pelo pensador russo Alexis Leontiev oferece subsídios para compreender a constituição humana a partir das relações sociais e apropriação do conhecimento. Nesse caminho, o desenvolvimento das ações do professor no
Camila Turati Pessoa +1 more
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