Results 61 to 70 of about 1,077,176 (268)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
A DOCÊNCIA NO ENSINO MÉDIO: UMA REFLEXÃO SOBRE OS PARADIGMAS INOVADORES
Linguagens, Educação e Sociedade, 2018 Esta pesquisa constitui-se em uma reflexão e pesquisa sobre a prática pedagógica, desenvolvida junto ao grupo de pesquisa PEFOP – Paradigmas Educacionais e Formação de Professores, de um Programa de Doutorado em Educação.
FLÁVIA LEAL KING BALECHE +2 more
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
TEACHER IDENTITIES DISCOURSES WITHIN ON-LINE COMMUNITIES ADRESSING TO REPLACEMENT TEACHERS
Travessias, 2013 On-line communitieshave been representedan alternativefor the dissemination of speech, access to information;citizenship;mobilizingof ordinary peopleto defend their interests, and especially in the constructionof identities.Theoretical frameworks used ...
Ana Paula Domingos Baladeli +1 more
doaj
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Вестник Кемеровского государственного университета, 2018 The research features Professor and surgeon V. F. Voyno-Yasenetsky who made an enormous contribution to the treatment of the wounded, disabled veterans and civilians during World War II.
S. V. Kozhevnikov
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
"O professor francês": Jean Gagé
Revista de História, 1975 Ao publicar-se o n° 103 da Revista de História, ocorreu-nos nele incluir algumas notas e reminiscências pessoais acerca de um dos mais importantes dentre os fundadores dos estudos históricos na Faculdade de Filosofia da Universidade de São Paulo: o prof.
Pedro Moacyr Campos
doaj