Results 81 to 90 of about 3,698,572 (312)
Synthesis and Properties of Ferrite-Based Nanoparticles
Nanomaterials, 2019 The work is dedicated to the study of the structural and optical characteristics, as well as the phase transformations, of ferrite nanoparticles of CeO2-Fe2O3.
Kayrat K. Kadyrzhanov +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Conocimiento de los profesores acerca de la segunda lengua y el currículo: una experiencia narrativa
, 2011 23 páginasThis study was carried out with a group of three teachers who work for the foreign languages de- partment of a private university in Colombia.
Mendieta Aguila, Jenny Alexandra
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LIBS of Low-Alloyed Lead Systems: Chemometric Data Processing and Quantitative Analysis
AnalyticaA probabilistic–deterministic design of experiments (PDDoE) approach was employed to optimize laser-induced breakdown spectroscopy (LIBS) parameters for the quantitative determination of minor components in lead-based alloys.
Vitaliy Fomin +8 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Una mirada retrospectiva y hacia el futuro para fortalecer la revista Profile
, 2020 Last February we held the XV PROFILE Symposium, an annual local event aimed at inviting teachers of English from different backgrounds to reflect on our profession, to share research results and innovations, and to highlight the importance of doing ...
Nieto-Cruz, María Claudia +1 more
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