Results 101 to 110 of about 3,619,354 (396)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The Distribution of Wealth. A Theory of Wages, Interest and Profits [PDF]

, 1902
Knut Wicksell, John B. Clark, J. A. Hobson   +2 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Utilization of in Vitro Anther Culture in Spelt Wheat Breeding

Plants, 2019
The efficiency of in vitro anther culture was screened in a full diallel population of four spelt wheat genotypes and ten F1 hybrids. Genotype dependency was observed based on the data of embryo-like structures (ELS), green-, albino plantlets.
Csaba Lantos, Szandra Purgel, Katalin Ács, Bernadett Langó, Lajos Bóna, Krisztina Boda, Ferenc Békés, János Pauk   +7 more
doaj   +1 more source

Flexible Outsourcing, Profit Sharing and Equilibrium Unemployment [PDF]

We analyze the questions associated with flexible outsourcing both with committed and flexible profit sharing under imperfect domestic labour markets. How does profit sharing influence flexible outsourcing?
Erkki Koskela, Jan König
core  

Profit-Sharing and Cooperative Production [PDF]

, 1892
L. L. Price
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

A General Theory of Sample Complexity for Multi-Item Profit Maximization

, 2018
The design of profit-maximizing multi-item mechanisms is a notoriously challenging problem with tremendous real-world impact. The mechanism designer's goal is to field a mechanism with high expected profit on the distribution over buyers' values ...
Balcan, Maria-Florina, Sandholm, Tuomas, Vitercik, Ellen   +2 more
core  

Inclusive governance in non-profit organisations [PDF]

, 2015
The study of private non-profit enterprises that offer general interest services is only at the start. The understanding of existing organisations resists an inclusive, public interest view of governance.
Borzaga, Carlo, Sacchetti, Silvia
core  

Rent and Profit [PDF]

, 1894
C.W. Macfarlane
openalex   +1 more source