Results 71 to 80 of about 3,619,354 (396)

Topological optimization of the axial compressor blade of aircraft gas turbine engine

open access: yesАвіаційно-космічна техніка та технологія
The requirements for the efficiency, reliability, and environmental friendliness of technical systems in modern mechanical engineering are constantly increasing.
Maryna Pikul   +3 more
doaj   +1 more source

Organization of measures for the prevention of neuropsychiatric complications of toxoplasmosis and toxocariasis in Ukraine

open access: yesAktualʹnaâ Infektologiâ, 2020
The article considers the issues of relevance, clinical manifestations, characteristics of the brain bioelectrical activity in patients with toxoplasmosis and toxocariasis, and measures for the prevention of neuropsychiatric complications of parasitic ...
O.V. Bobrova   +3 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Overcomplying for profit

open access: yesEnvironmental Economics and Policy Studies, 2005
To maximize their profit, multinationals can design and implement the same and toughest standard in all locations, regardless of domestic regulations. We discuss this kind of overcompliance and stress its underpinnings. Some potential extensions are suggested.
Grolleau, Gilles, Mzoughi, Naoufel
openaire   +4 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Not for the Profit, But for the Training? Gender Differences in Training in the For-Profit and Non-Profit Sectors [PDF]

open access: yesSSRN Electronic Journal, 2017
AbstractIn this article, we use Canadian‐linked employer–employee data to examine gender differences in receiving firm‐sponsored training. We find that women in the for‐profit sector are less likely to receive classroom training and receive fewer classroom training courses.
Benoit Dostie, Mohsen Javdani
openaire   +3 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Topological optimization of a ducted propeller of UAV

open access: yesАвіаційно-космічна техніка та технологія
The subject of this study is the minimization of the duct mass for a ducted propeller of UAV. The object of this study is a two-bladed ducted quadcopter propeller. The peripheral diameter of the propeller is 128 mm, and the hood is 2 mm thick.
Anton Balalaiev   +4 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Significance of the Stability of Fusarium Head Blight Resistance in the Variety Registration, Breeding, and Genetic Research of Winter Wheat Using Disease Index, Fusarium-Damaged Kernels, and Deoxynivalenol Contamination

open access: yesToxins
Fusarium head blight is one of the greatest threats to global wheat production. Despite the special attention paid by researchers to resistance genetics, the stability of resistance and the expression of its epidemiological relationships have not been ...
Ákos Mesterhazy   +4 more
doaj   +1 more source

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