Results 11 to 20 of about 778,828 (306)

Exosome complex orchestrates developmental signaling to balance proliferation and differentiation during erythropoiesis

open access: yeseLife, 2016
Since the highly conserved exosome complex mediates the degradation and processing of multiple classes of RNAs, it almost certainly controls diverse biological processes.
Skye C McIver   +6 more
doaj   +1 more source

WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion

open access: yesStem Cell Reports, 2017
Wilms' tumor suppressor 1 (WT1) plays an important role in cell proliferation and mesenchymal-epithelial balance in normal development and disease. Here, we show that following podocyte depletion in three experimental models, and in patients with focal ...
Natalya V. Kaverina   +8 more
doaj   +1 more source

C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells

open access: yesStem Cell Reports, 2017
The lymphoid-myeloid transdifferentiation potentials of members of the C/EBP family (C/EBPα, β, δ, and ε) were compared in v-Abl-immortalized primary B cells. Conversion of B cells to macrophages was readily induced by the ectopic expression of any C/EBP,
Branko Cirovic   +7 more
doaj   +1 more source

Origin of Basophils and Mast Cells

open access: yesAllergology International, 2009
Basophils and mast cells are major players in the progression of allergic disorders. Although both cell types originate from hematopoietic stem cells, their lineage commitment pathways and mechanisms have been unsolved issues in hematology.
Yojiro Arinobu   +2 more
doaj   +1 more source

CXCR4 pos circulating progenitor cells coexpressing monocytic and endothelial markers correlating with fibrotic clinical features are present in the peripheral blood of patients affected by systemic sclerosis [PDF]

open access: yes, 2008
There is still controversy regarding the role of circulating endothelial and progenitor cells (CECs/CEPs) in the pathogenesis of systemic sclerosis (SSc).
CAMPIONI, Diana   +8 more
core   +2 more sources

A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

open access: yesCell Reports, 2018
Summary: How are closely related lineages, including liver, pancreas, and intestines, diversified from a common endodermal origin? Here, we apply principles learned from developmental biology to rapidly reconstitute liver progenitors from human ...
Lay Teng Ang   +21 more
doaj   +1 more source

Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]

open access: yes, 2008
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H.   +10 more
core   +1 more source

Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration

open access: yeseLife, 2018
Under chronic or severe liver injury, liver progenitor cells (LPCs) of biliary origin are known to expand and contribute to the regeneration of hepatocytes and cholangiocytes.
Yasushi Miura   +11 more
doaj   +1 more source

Disappearance of the Progenitor of Supernova iPTF13bvn [PDF]

open access: yes, 2016
Supernova (SN) iPTF13bvn in NGC 5806 was the first Type Ib SN to have been tentatively associated with a progenitor candidate in pre-explosion images. We performed deep ultraviolet (UV) and optical Hubble Space Telescope (HST) observations of the SN site
Bersten, Melina C.   +15 more
core   +7 more sources

Some International Constitutional Aspects of the Palestine Case [PDF]

open access: yes, 1968
Cardiac tissue engineering via the use of stem cells is the future for repairing impaired heart function that results from a myocardial infarction.
Gelmi, Amy   +3 more
core   +2 more sources

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