Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig +10 more
wiley +1 more source
In Utero Electroporation Uncovers an Early-Differentiating Subset of Dentate Gyrus Progenitors. [PDF]
Shinohara HM, Takahashi T.
europepmc +1 more source
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim +11 more
wiley +1 more source
Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma. [PDF]
Veo B +11 more
europepmc +1 more source
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi +8 more
wiley +1 more source
Inactivation of CDK4/6, CDK2, and ERK in G1-phase triggers differentiation commitment. [PDF]
Sharma S, Berger H, Meyer T, Teruel MN.
europepmc +1 more source
Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials
This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker +5 more
wiley +1 more source
Immaturity-Dependent Hippocampal Neurogenic Promotion and Fate Shift by Low-Dose Propofol in Neonatal Mice Revealed Through Single-Nuclei RNA-Sequencing. [PDF]
Zhang W +6 more
europepmc +1 more source
Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source

