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Endothelium, 2006
The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
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The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
openaire +2 more sources
Progenitor cell transplantation
Drug and Therapeutics Bulletin, 1997Many leukaemias and solid cancers are now treated with high-dose chemotherapy, an approach made possible by techniques that bolster haematological recovery when bone marrow suppression occurs. The conventional way of reversing marrow suppression has been to give an autologous bone marrow transplant (cells aspirated from the patient's own marrow).
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Thymocyte progenitors in ageing
Immunology Letters, 1994The effect of ageing on thymocyte progenitors in the bone marrow was studied in an in vitro experimental model that permits T lymphocyte development. The model is based on co-culture of BM cells from young and old mice with lymphoid depleted fetal thymus explants.
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Pancreatic Cells and Their Progenitors
2006Both type 1 and type 2 diabetes patients would greatly benefit from transplantation of insulin-producing pancreatic beta cells; however, a severe shortage of transplantable beta cells is a major current limitation in the use of such therapy. Understanding the mechanisms by which beta cells are naturally formed is therefore a central challenge for ...
Seth J, Salpeter, Yuval, Dor
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New England Journal of Medicine, 2003
Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
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Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
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