Results 61 to 70 of about 778,828 (306)

Black Hole Hyperaccretion Inflow-outflow Model. I. Long And Ultra-long Gamma-ray Bursts

, 2017
Long-duration gamma-ray bursts (LGRBs) and ultra-LGRBs (ULGRBs) originate from collapsars, in the center of which a newborn rotating stellar-mass black hole (BH) surrounded by a massive accretion disk may form.
Gu, Wei-Min, Heger, Alexander, Liu, Tong, Song, Cui-Ying, Zhang, Bing   +4 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Profibrotic potential of Prominin-1⁺ epithelial progenitor cells in pulmonary fibrosis

Respiratory Research, 2011
Background In idiopathic pulmonary fibrosis loss of alveolar epithelium induces inflammation of the pulmonary tissue followed by accumulation of pathogenic myofibroblasts leading eventually to respiratory failures.
Lüscher Thomas F, Beck-Schimmer Beatrice, Matter Christian M, Moch Holger, Stein Sokrates, Germano Davide, Blyszczuk Przemyslaw, Eriksson Urs, Kania Gabriela   +8 more
doaj   +1 more source

Dynamics and neutrino signal of black hole formation in non-rotating failed supernovae. II. progenitor dependence

, 2008
We study the progenitor dependence of the black hole formation and its associated neutrino signals from the gravitational collapse of non-rotating massive stars, following the preceding study on the single progenitor model in Sumiyoshi et al. (2007).
H. Suzuki, K. Sumiyoshi, Keil W., S. Yamada, Yamada S.   +4 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue

Adipocyte, 2021
Some adipocytes are produced from bone marrow hematopoietic stem cells. In vitro studies previously indicated that these bone marrow-derived adipocytes (BMDAs) were generated from adipose tissue macrophage (ATM) that lose their hematopoietic markers and ...
Kathleen M. Gavin, Timothy M. Sullivan, Joanne K. Maltzahn, Jeremy T. Rahkola, Alistair S. Acosta, Wendy M. Kohrt, Susan M. Majka, Dwight J. Klemm   +7 more
doaj   +1 more source

An Intermediate Luminosity Transient in NGC300: The Eruption of a Dust-Enshrouded Massive Star

, 2009
[abridged] We present multi-epoch high-resolution optical spectroscopy, UV/radio/X-ray imaging, and archival Hubble and Spitzer observations of an intermediate luminosity optical transient recently discovered in the nearby galaxy NGC300. We find that the
A. K. Dupree, A. M. Diamond-Stanic, A. M. Soderberg, Berger, Berger, Bond, Bond, C. A. Tremonti, C. Fransson, Chevalier, D. C. Leonard, E. Berger, Gieren, Humphreys, I. B. Thompson, I. I. Ivans, J. H. Debes, J. Simmerer, Monard, Munari, Ofek, Prieto, Prieto, R. A. Chevalier, R. J. Foley, Schlegel, Smith, Stockdale, Thompson, Waxman   +29 more
core   +1 more source

The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. [PDF]

, 2014
BackgroundIdentification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology.ResultsWe demonstrate that conditional ...
Band, Hamid, Band, Vimla, Edwards, Emily, Kopp, Janel L, Malhotra, Gautam K, Naramura, Mayumi, Sander, Maike, Zhao, Xiangshan   +7 more
core   +2 more sources

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Direct and indirect RANK and CD40 signaling regulate the maintenance of thymic epithelial cell frequency and properties in the adult thymus

Frontiers in Immunology
Medullary thymic epithelial cells (mTECs) play a crucial role in suppressing the onset of autoimmunity by eliminating autoreactive T cells and promoting the development of regulatory T cells in the thymus.
Mio Hayama, Mio Hayama, Hiroto Ishii, Hiroto Ishii, Maki Miyauchi, Maki Miyauchi, Masaki Yoshida, Naho Hagiwara, Wataru Muramtatu, Wataru Muramtatu, Kano Namiki, Kano Namiki, Rin Endo, Rin Endo, Takahisa Miyao, Nobuko Akiyama, Nobuko Akiyama, Taishin Akiyama, Taishin Akiyama   +18 more
doaj   +1 more source