Results 61 to 70 of about 10,838,787 (366)

Altered Erythro-Myeloid Progenitor Cells Are Highly Expanded in Intensively Regenerating Hematopoiesis

Frontiers in Cell and Developmental Biology, 2020
Regeneration of severely damaged adult tissues is currently only partially understood. Hematopoietic tissue provides a unique opportunity to study tissue regeneration due to its well established steady-state structure and function, easy accessibility ...
Kateřina Faltusová, Chia-Ling Chen, Tomáš Heizer, Tomáš Heizer, Martin Báječný, Katarina Szikszai, Petr Páral, Filipp Savvulidi, Nicol Renešová, Nicol Renešová, Emanuel Nečas, Emanuel Nečas   +11 more
doaj   +1 more source

Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

Genes & Development, 2014
Here, Li et al. show that inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell (HSPC) formation. HSCs from aorta/gonad/mesonephros (AGM) regions of midgestation mouse embryos expressed a robust innate immune/inflammatory ...
Yan Li, Virginie Esain, Li Teng, Jian Xu, W. Kwan, Isaura M. Frost, Amanda D Yzaguirre, Xiongwei Cai, Mauricio Cortes, Marijke W. Maijenburg, Joanna Tober, E. Dzierzak, S. Orkin, Kai Tan, Trista E North, N. Speck   +15 more
semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Progenitor-Based Cell Biological Aspects of Neocortex Development and Evolution

Frontiers in Cell and Developmental Biology, 2022
During development, the decision of stem and progenitor cells to switch from proliferation to differentiation is of critical importance for the overall size of an organ. Too early a switch will deplete the stem/progenitor cell pool, and too late a switch
Samir Vaid, Wieland B. Huttner
doaj   +1 more source

Search for the preadipocyte progenitor cell [PDF]

Journal of Clinical Investigation, 2006
An increase in adipocyte number is a major contributor to the increase in adipose tissue mass that is characteristic of obesity. The identity and regulation of the adipocyte precursor cell (or preadipocyte) and the preadipocyte precursor cell (or progenitor cell) have been intensely studied for many years.
Gary J. Hausman, Dorothy B. Hausman
openaire   +3 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Differential number of CD34+, CD133+ and CD34+/CD133+ cells in peripheral blood of patients with congestive heart failure

European Journal of Medical Research, 2009
Background Endothelial progenitor cells (EPC) which are characterised by the simulateous expression of CD34, CD133 and vascular endothelial growth receptor 2 (VEGF 2) are involved in the pathophysiology of congestive heart failure (CHF) and their number ...
Fritzenwanger M, Lorenz F, Jung C, Fabris M, Thude H, Barz D, Figulla HR   +6 more
doaj   +1 more source

Endothelial progenitor cells in atherosclerosis [PDF]

Frontiers in Bioscience, 2012
Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial homoeostasis and in the process of new vessel formation. Experimental and clinical studies have shown that atherosclerosis is associated with reduced numbers and dysfunction of EPCs; and that medications alone are able to partially reverse the impairment of EPCs in ...
Anthony Virtue, Xinyuan Li, Meghana Pansuria, Jun Zhou, Xiaofeng Yang, Hong Wang, Ren Gong, Fuyong Du, Xiao Huang   +8 more
openaire   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Flow Cytometric Determination of Circulating Progenitor Cells in Patients With Pulmonary Arterial Hypertension: A Systematic Review

Pulmonary Circulation
Pulmonary arterial hypertension (PAH) is characterized by progressive narrowing and obliteration of distal, pre‐capillary pulmonary vessels. Yet, noninvasive biomarkers that reflect this disease‐defining process are lacking.
Kimia Heydari, Carrie Johnson, I. Diane Cooper, Kadija Hersi, Carl Tanba, Junfeng Sun, Michael A. Solomon, Jason M. Elinoff   +7 more
doaj   +1 more source