Results 41 to 50 of about 554,381 (309)

Molecular recording of mammalian embryogenesis. [PDF]

, 2019
Ontogeny describes the emergence of complex multicellular organisms from single totipotent cells. This field is particularly challenging in mammals, owing to the indeterminate relationship between self-renewal and differentiation, variation in progenitor
Adamson, Britt, Chan, Michelle M, Grosswendt, Stefanie, Jones, Matthew G, Jost, Marco, Khodaverdian, Alex, Kretzmer, Helene, Meissner, Alexander, Norman, Thomas M, Quinn, Jeffrey J, Smith, Zachary D, Weissman, Jonathan S, Yang, Dian, Yosef, Nir   +13 more
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HIV reprograms progenitor cells [PDF]

Science, 2017
HIV Survival rates of patients with HIV have improved enormously as a result of antiretroviral therapy, but increased life expectancy is now associated with a high risk of comorbidities. HIV–1-associated chronic obstructive pulmonary disease (COPD) often manifests as emphysema, originating around the airways and extending into lung tissue. Chung et al.
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Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. [PDF]

, 2015
The field of tissue engineering entered a new era with the development of human pluripotent stem cells (hPSCs), which are capable of unlimited expansion whilst retaining the potential to differentiate into all mature cell populations.
Brafman, David, Bush, Kevin T, Cutts, Josh, Gaasterland, Terry, Kumar, Nathan, Nigam, Sanjay K, Richter, Jenna, Trujillo, Cleber, Willert, Karl   +8 more
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Human Endothelial Progenitor Cells [PDF]

Cold Spring Harbor Perspectives in Medicine, 2011
Human endothelial progenitor cells (EPCs) have been generally defined as circulating cells that express a variety of cell surface markers similar to those expressed by vascular endothelial cells, adhere to endothelium at sites of hypoxia/ischemia, and participate in new vessel formation.
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Proliferation versus Differentiation: Redefining Retinoic Acids Role. [PDF]

, 2018
Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al.
Mosher, Kira, SCHAFFER, David
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Mast cell-committed progenitors [PDF]

Proceedings of the National Academy of Sciences, 2005
Mast cells play a central role in the development of the immediate hypersensitivity reaction. This reaction occurs within minutes after the recognition of an antigen by IgE antibodies bound to mast cells in sensitized individuals. Although diseases based on the immediate hypersensitivity reaction, such as allergic rhinitis, bronchial asthma, and ...
Yukihiko, Kitamura, Akihiko, Ito
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Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

eLife, 2023
Polycomb repressive complex (PRC) 1 regulates stem cell fate by mediating mono-ubiquitination of histone H2A at lysine 119. While canonical PRC1 is critical for hematopoietic stem and progenitor cell (HSPC) maintenance, the role of non-canonical PRC1 in ...
Yaeko Nakajima-Takagi, Motohiko Oshima, Junichiro Takano, Shuhei Koide, Naoki Itokawa, Shun Uemura, Masayuki Yamashita, Shohei Andoh, Kazumasa Aoyama, Yusuke Isshiki, Daisuke Shinoda, Atsunori Saraya, Fumio Arai, Kiyoshi Yamaguchi, Yoichi Furukawa, Haruhiko Koseki, Tomokatsu Ikawa, Atsushi Iwama   +17 more
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Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. [PDF]

, 2018
The mammary epithelium depends on specific lineages and their stem and progenitor function to accommodate hormone-triggered physiological demands in the adult female.
Abe, Akalin, Alison E. Casey, Ankit Sinha, Asselin-Labat, Buenrostro, Cardiff, Cerami, Cheryl Arrowsmith, Chlebowski, Cox, Cox, Dalia Barsyte-Lovejoy, Daniel De Carvalho, Deugnier, Dos Santos, Edgar, Eirew, Eirew, Eisen, Erik Drysdale, Gary Bader, Gascard, Genevieve Deblois, Gu, Hal Berman, Heinz, Hennighausen, Herschkowitz, Hu, Hui Fang, Huston, Hyeyeon Kim, Ignatchenko, Jackson, Jennifer Cruickshank, Joshi, Joshi, Joshi, Julie Livingstone, Kaltenborn, Kauff, Kelsey, Kendrick, Kiechl, Kislinger, Koboldt, Kotsopoulos, Krueger, Kucera, Labarge, Li, Lim, Lim, Lin, Loenen, Lucas, Lydon, Marotti, Maruyama, Mathieu Lupien, McLean, Meissner, Merico, Michailidou, Michalak, Mohammed, Molyneux, Mona Shehata, Nguyen, Pal, Pathania, Paul C. Boutros, Paul Waterhouse, Pei, Pellacani, Pirashaanthy Tharmapalan, Rajat Singhania, Rama Khokha, Reimand, Rios, Rios, Rugg-Gunn, Ruth Isserlin, Schimanski, Shackleton, Shannon, Shehata, Shiah, Shu, Sigl, Smith, Smyth, Stefan Hofer, Stefan Knapp, Stingl, Storey, Stunnenberg, Subramanian, Swneke Bailey, Thomas Kislinger, Tiago Medina, Tomasetti, van Amerongen, Van Keymeulen, Van Keymeulen, Visvader, Wang, Wojtowicz, Wuidart, Yu-Jia Shiah, Zhang   +111 more
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Circulating endothelial progenitor cells [PDF]

British Journal of Cancer, 2005
Angiogenesis research investigates the formation of new blood vessels in wound healing, tumour growth and embryonic development. Circulating, bone marrow-derived endothelial progenitor cells (EPCs) were first described 8 years ago, yet the exact nature of these endothelial precursor cells remains unclear.
Garmy-Susini, B, Varner, J A
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Myocardial Ischemia and Mobilization of Circulating Progenitor Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThe response of progenitor cells (PCs) to transient myocardial ischemia in patients with coronary artery disease remains unknown. We aimed to investigate the PC response to exercise‐induced myocardial ischemia (ExMI) and compare it to flow ...
Muhammad Hammadah, Ayman Samman Tahhan, Ibhar Al Mheid, Kobina Wilmot, Ronnie Ramadan, Bryan R. Kindya, Heval M. Kelli, Wesley T. O'Neal, Pratik Sandesara, Samaah Sullivan, Zakaria Almuwaqqat, Malik Obideen, Naser Abdelhadi, Ayman Alkhoder, Pratik M. Pimple, Oleksiy Levantsevych, Kareem H. Mohammed, Lei Weng, Laurence S. Sperling, Amit J. Shah, Yan V. Sun, Brad D. Pearce, Michael Kutner, Laura Ward, J. Douglas Bremner, Jinhee Kim, Edmund K. Waller, Paolo Raggi, David Sheps, Viola Vaccarino, Arshed A. Quyyumi   +30 more
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