The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. [PDF]
BackgroundIdentification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology.ResultsWe demonstrate that conditional ...
Band, Hamid +7 more
core +2 more sources
The Musashi family RNA-binding proteins in stem cells
The Musashi family is an evolutionarily conserved group of RNA-binding proteins. In mammal, two members of the group, Msi1 and Msi2, have been identified to date.
Horisawa Kenichi +3 more
doaj +1 more source
The mammalian central nervous system (CNS) develops from multipotent progenitor cells, which proliferate and differentiate into the various cell types of the brain and spinal cord.
Janelle M.P. Pakan +1 more
doaj +1 more source
Improving the viability of tissue‐resident stem cells using an organ‐preservation solution
Human clinical specimens are a valuable source of tissue‐resident stem cells, but such cells need to be collected immediately after tissue collection. To extend the timescale for collection from fresh human samples, we developed a new extracellular fluid
Takaya Suzuki +8 more
doaj +1 more source
Sex Differences in Circulating Progenitor Cells
BackgroundLower levels of circulating progenitor cells (PCs) reflect impaired endogenous regenerative capacity and are associated with aging, vascular disease, and poor outcomes.
Matthew L. Topel +9 more
doaj +1 more source
At early developmental stages, limb bud mesodermal undifferentiated cells are morphologically indistinguishable. Although the identification of several mesodermal skeletal progenitor cell populations has been recognized, in advanced stages of limb ...
Jessica Cristina Marín-Llera +3 more
doaj +1 more source
Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke. [PDF]
Focal stroke is a disabling disease with lifelong sensory, motor and cognitive impairments. Given the paucity of effective clinical treatments, basic scientists are developing novel options for protection of the affected brain and regeneration of lost ...
Carmichael, S Thomas, Moshayedi, Pouria
core +1 more source
Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]
Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Aicher, A +8 more
core +1 more source
Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. [PDF]
Progenitor cells are considered an important cell of origin of human malignancies. However, there has not been any single gene that can define mammary bipotential progenitor cells, and as such it has not been possible to use genetic methods to introduce ...
Bu, W +10 more
core +2 more sources
The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C +15 more
core +2 more sources

