Results 161 to 170 of about 14,020 (216)

Disease pathogenicity in Hutchinson-Gilford progeria syndrome mice: insights from lung-associated alterations. [PDF]

Mol Med
Wang J, Guan Y, Wang Y, Tan J, Cao Z, Ding Y, Gao L, Fu H, Chen X, Lin J, Shen N, Fu X, Wang F, Mao J, Hu L.   +14 more
europepmc   +1 more source

RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria. [PDF]

Mol Cell
Behera AK, Kim JJ, Kordale S, Pekovic F, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Valkov E, Gonatopoulos-Pournatzis T.   +13 more
europepmc   +1 more source

The unfolded protein response in progeria arteries originates from non-endothelial cell types. [PDF]

Life Sci Alliance
Silva RA, Sarigol F, Karagöz GE, Osmanagic-Myers S, Foisner R.   +4 more
europepmc   +1 more source

Cardiomyocyte-Restricted Expression of Progerin Confers Cardiac Hypertrophy. [PDF]

Circ Res
Subati T, Buehler DP, Zhong L, Miller FJ, Agrawal V, Brown JD.   +5 more
europepmc   +1 more source

Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice. [PDF]

Int J Mol Sci
Krüger P, Schroll M, Fenzl FQ, Hartinger R, Lederer EM, Görlach A, Gordon LB, Cavalcante P, Iacomino N, Rathkolb B, Pimentel JAA, Östereicher M, Spielmann N, Wolf CM, de Angelis MH, Djabali K.   +15 more
europepmc   +1 more source

Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis. [PDF]

Aging (Albany NY)
Fenzl FQ, Lederer EM, Brumma L, Krüger P, Schroll M, Wilming F, Djabali K.   +6 more
europepmc   +1 more source

Vascular Smooth Muscle–Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome [PDF]

Circulation, 2018
Background: Progerin, an aberrant protein that accumulates with age, causes the rare genetic disease Hutchinson-Gilford progeria syndrome (HGPS). Patients who have HGPS exhibit ubiquitous progerin expression, accelerated aging and atherosclerosis, and ...
Magda R Hamczyk, Ricardo Villa-Bellosta, Pilar Gonzalo   +2 more
exaly   +6 more sources