Results 131 to 140 of about 13,996 (187)

Estimation of Subtype‐Specific Tumour Growth Rate Distributions and Interval Cancer Proportions in Breast Cancer Using Biology‐Inspired Natural History Models

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Breast cancer progression varies across molecular subtypes, influencing detection rates and prognosis. Differences in the proportion of interval cancers (PIC)—cancers detected symptomatically between scheduled screening rounds—have been observed across subtypes, likely reflecting heterogeneity in tumour growth dynamics. We applied a continuous‐
Letizia Orsini   +3 more
wiley   +1 more source

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer   +2 more
wiley   +1 more source

Cardiometabolic Health and Risk of Breast Cancer Subtypes Among US Black Women

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT In the United States (US), cardiometabolic conditions and aggressive breast cancers are both more common among Black women than White women. Using data from 57,453 participants in the Black Women's Health Study (BWHS), we prospectively evaluated associations of body mass index (BMI), Type 2 diabetes, hypertension, and hypercholesterolemia with
Yifei Shan   +4 more
wiley   +1 more source

Messages clés

open access: yes
Les SSRI, SNRI et la mirtazapine traitent efficacement la dépression périménopausique tout en améliorant le sommeil, l'anxiété et les symptômes vasomoteurs. L'œstrogène associé à la progestérone micronisée améliore les symptômes vasomoteurs et peut avoir
Katie Unverferth
core   +1 more source

The Epithelial Epigenome: A Unified Platform for Cancer Risk Prediction and Prevention Monitoring

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Intrinsic biological processes and carcinogenic exposures leave cumulative DNA methylation (DNAme) imprints in epithelial cells. These changes reflect cellular composition, replicative/mitotic age and impaired differentiation capacity, and arise long before clinically detectable cancer, consistent with the concept of field cancerisation ...
Martin Widschwendter
wiley   +1 more source

Suivi des chaleurs par dosage de la progestérone chez la chienne (comparaison d'une méthode ELISA rapide (ovuchek premate, vétoquinol diagnostics) à la radio-immunologie)

open access: yes, 2003
Une bonne connaissance des modifications anatomiques et hormonales chez la chienne au cours des chaleurs est indispensable pour une maîtrise optimale de sa reproduction.
HAUBOURDIN, Bénédicte   +1 more
core  

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev   +3 more
wiley   +1 more source

Effets d'un antagoniste de la progestérone sur l'expression de quatre protéines d'intérêt dans l'oviducte en période péri-ovulatoire chez la chienne

open access: yes, 2014
The reproductive physiology of female dogs differs from that of other mammals, particularly regarding oocyte maturation. Indeed, in bitches, immature oocytes (germinal vesicles) are released and become metaphase II oocytes in the oviduct, two to three ...
Vialle, Laure
core  

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella   +5 more
wiley   +1 more source

Intérêt de la courbe de progestéronémie: Doser la progestérone permet de réaliser un suivi reproducteur plus précis. Connaître la date d'ovulation permet de déterminer la date de mise bas.

open access: yes
National audienceLa progestérone est une hormone très robuste mais pas si facile à doser. Son dosage nécessite une machine fiable et une rigueur dans la façon de préparer le prélèvement (même type de tubes...).
Rosset, Emilie
core  

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