Results 31 to 40 of about 362,542 (345)

The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk

Microbiome, 2017
Preterm birth is the primary cause of infant death worldwide. A short cervix in the second trimester of pregnancy is a risk factor for preterm birth. In specific patient cohorts, vaginal progesterone reduces this risk.
L. Kindinger, P. Bennett, Yun S. Lee, J. Marchesi, Ann Smith, Stefano Cacciatore, E. Holmes, J. Nicholson, T. Teoh, D. MacIntyre   +9 more
semanticscholar   +1 more source

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

Genes & Development, 1995
Although progesterone has been recognized as essential for the establishment and maintenance of pregnancy, this steroid hormone has been recently implicated to have a functional role in a number of other reproductive events.
J. Lydon, C. Funk, Shiala K. Mani, Angela R. Hughes, G. Shyamala, Orla M. Connee ly   +5 more
semanticscholar   +1 more source

The GABAA antagonist bicuculline attenuates progesterone-induced memory impairments in middle-aged ovariectomized rats

Frontiers in Aging Neuroscience, 2015
In women, high levels of natural progesterone have been associated with detrimental cognitive effects via the maternal amnesia phenomenon as well as in controlled experiments.
B. Blair Braden, B. Blair Braden, B. Blair Braden, Melissa L. Kingston, Elizabeth eWhitton, Courtney N. Lavery, Candy W.S. Tsang, Heather Allyson Bimonte-Nelson, Heather Allyson Bimonte-Nelson   +8 more
doaj   +1 more source

Effect of slightly elevated progesterone on hCG trigger day on clinical pregnancy rate in GnRH-ant IVF/ICSI cycles

Reproductive Health, 2022
Background It was been agreed that significantly elevated progesterone level on the hCG trigger day have detrimental effect on clinical outcomes in IVF/ICSI cycles.
Jing Zhao, Jie Hao, Bin Xu, Yonggang Wang, Yanping Li   +4 more
doaj   +1 more source

Initiating luteal phase support with sc progesterone based on low serum progesterone on the transfer day in true natural cycle frozen embryo transfers

Frontiers in Endocrinology, 2023
IntroductionConcerning contemporary in-vitro fertilisation (IVF) practice, the use of frozen embryo transfer (FET) cycles has become more common than fresh transfers.
Cem Demirel, Pınar Özcan, Fırat Tülek, Hikmet Tunç Timur, Özge Pasin   +4 more
doaj   +1 more source

Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta‐analysis of individual patient data

Ultrasound in Obstetrics and Gynecology, 2017
To assess the efficacy of vaginal progesterone for the prevention of preterm birth and neonatal morbidity and mortality in asymptomatic women with a twin gestation and a sonographic short cervix (cervical length ≤ 25 mm) in the mid‐trimester.
Roberto Romero, A. CONDE-AGUDELO, A. CONDE-AGUDELO, Waleed El-refaie, L. Rode, L. Rode, M. L. Brizot, E. Cetingoz, V. Serra, E. Fonseca, M. Abdelhafez, A. Tabor, A. Tabor, A. Perales, S. Hassan, S. Hassan, K. Nicolaides   +16 more
semanticscholar   +1 more source

Progesterone Actions During Central Nervous System Development

Frontiers in Neuroscience, 2019
Although progesterone is a steroid hormone mainly associated with female reproductive functions, such as uterine receptivity and maintenance of pregnancy, accumulating data have shown its physiological actions to extend to several non-reproductive ...
J. C. González-Orozco, I. Camacho-Arroyo   +1 more
semanticscholar   +1 more source

Vaginal progesterone decreases preterm birth ≤ 34 weeks of gestation in women with a singleton pregnancy and a short cervix: an updated meta‐analysis including data from the OPPTIMUM study

Ultrasound in Obstetrics and Gynecology, 2016
To evaluate the efficacy of vaginal progesterone administration for preventing preterm birth and perinatal morbidity and mortality in asymptomatic women with a singleton gestation and a mid‐trimester sonographic cervical length (CL) ≤ 25 mm.
Roberto Romero, K. Nicolaides, A. CONDE-AGUDELO, J. O'Brien, E. Cetingoz, E. Fonseca, G. Creasy, S. Hassan, S. Hassan   +8 more
semanticscholar   +1 more source

Progesterone receptor modulates estrogen receptor-α action in breast cancer

Nature, 2015
Progesterone receptor (PR) expression is used as a biomarker of oestrogen receptor-α (ERα) function and breast cancer prognosis. Here we show that PR is not merely an ERα-induced gene target, but is also an ERα-associated protein that modulates its ...
Hisham Mohammed, I. A. Russell, R. Stark, O. Rueda, Theresa E. Hickey, G. Tarulli, Aurélien A. Sérandour, S. Birrell, A. Bruna, Amel Saadi, S. Menon, J. Hadfield, Michelle Pugh, Ganesh V. Raj, Gordon D. Brown, C. D’Santos, Jessica L. L. Robinson, Grace O. Silva, Rosalind Launchbury, Charles M. Perou, J. Stingl, C. Caldas, W. Tilley, Jason S. Carroll   +23 more
semanticscholar   +1 more source

Serum Progesterone Concentration and Ongoing Pregnancy Rate in Frozen-Thawed Embryo Transfers with Intramuscular Plus Vaginal Progesterone Administration for Endometrial Preparation

Journal of Kerman University of Medical Sciences, 2022
Background: Insufficient serum progesterone level in the implantation phase may reduce the rate of pregnancy during freeze embryo transfer (FET) cycles.
Marzieh Mehrafza
doaj   +1 more source