IKBKE modulates autophagy and progestin resistance in endometrial cancer [PDF]
Frontiers in OncologyBackground/objectivesEndometrial cancer (EC) is a prevalent malignancy in women, with up to 16% of cases diagnosed in individuals under 40 years old. Progestin-based therapies are essential for fertility preservation in EC patients, but resistance to ...
Jiahui Wang, Xianchao Kong
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Dharma Raflesia, 2022 Post partum atau masa nifas adalah masa setelah keluarnya plasenta sampai alat-alat reproduksi pulih seperti sebelum hamil berlangsung 6 minggu. Pil progestin merupakan alat kontrasepsi yang aman untuk ibu post partum.
Dara Himalaya, Deni Maryani
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Verteporfin reverses progestin resistance through YAP/TAZ-PI3K-Akt pathway in endometrial carcinoma
Cell Death Discovery, 2023 Progestin resistance is a problem for patients with endometrial carcinoma (EC) who require conservative treatment with progestin, and its underlying mechanisms remain unclear. YAP and TAZ (YAP/TAZ), downstream transcription coactivators of Hippo pathway,
Lina Wei +9 more
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Frontiers in Endocrinology, 2023 ObjectiveProgestin based therapy is the preferred option for fertility-sparing treatment of reproductive-age women with preserved fertility in endometrial hyperplasia (EH) or early endometrial cancer (EEC).
Fengping Shao, Yinguang Li, Yunhe Zhao
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Does progestin-only contraceptive use after pregnancy affect recovery from pelvic girdle pain? A prospective population study. [PDF]
PLoS ONE, 2017 To estimate associations of progestin-only contraceptives with persistent pelvic girdle pain 18 months after delivery.Prospective population based cohort study during the years 2003-2011.
Elisabeth Krefting Bjelland +6 more
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Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
, 2020 Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
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Germany Endometriosis Pattern Changes; Prevalence and Therapy over 2010 and 2019 Years: A Retrospective Cross Sectional Study [PDF]
International Journal of Fertility and Sterility, 2022 Background: The aim of this study was to investigate whether the prevalence and the therapy patterns of endometriosis differ in 2010 and 2019. Materials and Methods: This retrospective cross-sectional study was based on the data from the IQVIA Disease ...
Jacob Goehring +3 more
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Vitamin D and Mitosis Evaluation in Endometriosis: A Step toward Discovering the Connection?
Biomedicines, 2023 (1) Background: The effects of serum vitamin D levels, the vitamin D receptor (VDR), and phosphohistone H3 (PHH3) in endometriosis were investigated in two cohorts of women with this pathology: those receiving hormonal treatment and those without ...
Daniela Roxana Matasariu +9 more
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Frontiers in Genetics, 2022 Objective: The aim of this study was to establish predictive models based on the molecular profiles of endometrial lesions, which might help identify progestin-insensitive endometrial atypical hyperplasia (EAH) or endometrioid endometrial cancer (EEC ...
Jia-Li Hu +11 more
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Effects of Etisterone and Contrasmine pills on clinical and biochemical findings of hyperandrogenism and metabolic parameters of patients with polycystic ovary syndrome: A randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020 Introduction: Nowadays, selection of a contraceptive with most anti-androgenic effects is an important challenge in treatment of patients with polycystic ovary syndrome (PCOS).
Mina Amiri +3 more
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