Results 121 to 130 of about 30,715 (288)
Progestins and uterine leiomyoma
Gynecological Endocrinology, 1999 Myomas are the most frequent benign gynecological tumors and are responsible for several symptoms and complaints. Their etiology is unknown and their pathology and proliferation is poorly understood. Besides the importance of estrogens for development and growth of the myoma, progesterone seems to play an important role in the modulation of mitotic ...
openaire +2 more sources
Sugammadex interference with serum progesterone measurement: an in‐vitro study
Anaesthesia, EarlyView.Summary Introduction Sugammadex may interfere with serum progesterone immunoassays, potentially rendering measured concentrations and resulting recommendations unreliable. Methods We investigated the effect of a range of sugammadex concentrations on serum progesterone concentrations in samples from pre‐menopausal female volunteers.
Tamblyn Devoy +5 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang +6 more
wiley +1 more source
When CO<sub>2</sub> sensing fails: Protective effects of sex hormones and potential mechanisms. [PDF]
J NeuroendocrinolAbstract Breathing movements driven by the brainstem rhythmogenic neural networks rely on chemosensory inputs to produce a motor output that is homeostatically adjusted to the prevailing metabolic demand. The central CO2 chemoreflex is a critical component of respiratory neural circuitry, as defects in these sensors cause hypoventilation syndromes ...
Janes TA, Cardani S, Pagliardini S.
europepmc +2 more sources
Gynecological Endocrinology, 2007 Progestins exert their progestational activity by binding to the progesterone receptor (form A, the most active and form B, the less active) and may also interact with other steroid receptors (androgen, glucocorticoid, mineralocorticoid, estrogen). They can have important effects in other tissues besides the endometrium, including the breast, liver ...
openaire +2 more sources
Progestin potency – Assessment and relevance to choice of oral contraceptives
, 2011 Objectives: To evaluate current information on the potency of older and newer progestins and the relevance to oral contraceptive (OC) use. Methods: A medline search back to the last review (1985) was conducted.
Norman Goldstuck
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose Hormonal replacement therapy (HRT) in postmenopausal women appears to affect glaucoma risk, but findings are inconsistent. We aimed to explore whether the use of postmenopausal HRT plays a role in glaucoma development in Finland. Methods The main outcome variable was glaucoma incidence measured by initiation of special reimbursement ...
Sirpa Loukovaara, Jari Haukka
wiley +1 more source
PR binding associated with progestin responsive genes.
, 2012 Gene expression profiles in T-47D and AB32 cells were determined at 2, 6 and 24 h after treatment with 10 nM ORG2058. Transcripts that were significantly differentially expressed at 2, 6 and/or 24 h, compared to untreated controls, were considered ...
Christine L. Clarke (169388) +1 more
core +1 more source
Basal body temperature as a biomarker of reproductive state in ewes: A multi‐method comparison
Australian Veterinary Journal, EarlyView.This study quantified body temperature dynamics throughout reproductive stages in crossbred ewes based on complementary monitoring techniques. Five ewes from a semi‐extensive farming system were included in two sub‐trials: animals were first assessed in the prepubertal stage and, subsequently, an oestrous cycle was induced by intravaginal progesterone ...
E Pérez‐García +4 more
wiley +1 more source