Treating age‐related loss of muscle mass and function: Where should we be focusing?
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham +4 more
wiley +1 more source
A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol. [PDF]
Coelingh Bennink HJT +9 more
europepmc +1 more source
ABSTRACT Introduction Hypoactive Sexual Desire Disorder (HSDD) is characterized by a long‐term decrease in sexual desire (low‐libido) causing personal distress. HSDD predominantly affects post‐menopausal women or following oophorectomy. Despite the clear indication that testosterone action could overcome the symptoms of HSDD by elevating testosterone ...
Adrian Heald +10 more
wiley +1 more source
Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts. [PDF]
Wageh M, Kamal M, Parise G.
europepmc +1 more source
ABSTRACT Context Adult data indicate that hypogonadism is underdiagnosed and undertreated in Prader‐Willi Syndrome (PWS). Objectives We aimed to describe the spectrum of pubertal development, and the diagnosis and treatment of hypogonadism in paediatric/adolescent patients with PWS. Design/Patients A retrospective cohort study of patients with PWS aged
Helen Nguyen +2 more
wiley +1 more source
Editorial: Recent advances in thromboembolism and oral contraceptives. [PDF]
Morimont L, Foidart JM.
europepmc +1 more source
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Multiple congenital malformations in a litter of feline fetuses associated with gestational exposure to a synthetic estrus-suppressing progestin. [PDF]
Lacerda WK +5 more
europepmc +1 more source
ABSTRACT Purpose The prognostic impact of the interval between the most recent childbirth and breast cancer diagnosis remains insufficiently defined, particularly when breast cancer diagnosed during pregnancy (PrBC) is distinguished from postpartum breast cancer (PPBC).
Liying Wang +5 more
wiley +1 more source
Pharmacodynamic interaction analysis of dydrogesterone, progesterone, and estradiol in combination-progestin HRT frozen embryo transfer: a prospective clinical cohort study. [PDF]
Eggersmann TK +13 more
europepmc +1 more source

