Results 11 to 20 of about 21,243,142 (99)

Construction and Validation of a Ferroptosis-Related Prognostic Model for Gastric Cancer

Journal of Oncology, 2021
Background Gastric cancer (GC), an extremely aggressive tumor with a very different prognosis, is the third leading cause of cancer-related mortality. We aimed to construct a ferroptosis-related prognostic model that can be distinguished prognostically ...
Xiaotao Jiang, Qiaofeng Yan, Linling Xie, Shijie Xu, Kailin Jiang, Jiahua Huang, Yi Wen, Yanhua Yan, Junhui Zheng, Shuting Tang, Kechao Nie, Zhihua Zheng, Jing-lin Pan, Peng Liu, Yuancheng Huang, Xingrui Yan, Y. Zou, Xuan Chen, Fengbin Liu, Peiwu Li, Kunhai Zhuang   +20 more
semanticscholar   +1 more source

Tumor Mutation Burden, Immune Cell Infiltration, and Construction of Immune-Related Genes Prognostic Model in Head and Neck Cancer

International Journal of Medical Sciences, 2021
Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, and the prognosis of HNSCC remains bleak. Numerous studies revealed that the tumor mutation burden (TMB) could predict the survival outcomes of a ...
Ai-min Jiang, Mengdi Ren, Na Liu, Huan Gao, Jingjing Wang, Xiaoqiang Zheng, Xiao Fu, Xuan Liang, Zhiping Ruan, T. Tian, Yu Yao   +10 more
semanticscholar   +1 more source

A Novel Prognostic Model Based on Ferroptosis-Related Gene Signature for Bladder Cancer

Frontiers in Oncology, 2021
Background Bladder cancer (BC) is a molecular heterogeneous malignant tumor; the treatment strategies for advanced-stage patients were limited. Therefore, it is vital for improving the clinical outcome of BC patients to identify key biomarkers affecting ...
Libo Yang, Chunyan Li, Yang Qin, Guoyin Zhang, Bin Zhao, Ziyuan Wang, You-guang Huang, Yong Yang   +7 more
semanticscholar   +1 more source

Prediction of Outcome in Patients With Chronic Lymphocytic Leukemia Treated With Ibrutinib: Development and Validation of a Four-Factor Prognostic Model.

Journal of Clinical Oncology, 2020
PURPOSE Randomized trials established the superiority of ibrutinib-based therapy over chemoimmunotherapy in chronic lymphocytic leukemia. Durability of progression-free survival (PFS) with ibrutinib can vary by patient subgroup.
I. Ahn, X. Tian, D. Ipe, M. Cheng, M. Albitar, L. Claire Tsao, Lei Zhang, Wanlong Ma, S. E. Herman, E. Gaglione, S. Soto, J. Dean, A. Wiestner   +12 more
semanticscholar   +1 more source

The construction and validation of an RNA binding protein-related prognostic model for bladder cancer

BMC Cancer, 2021
Background RNA-binding proteins (RBPs) play crucial and multifaceted roles in post-transcriptional regulation. While RBPs dysregulation is involved in tumorigenesis and progression, little is known about the role of RBPs in bladder cancer (BLCA ...
Fengxia Chen, Qingqing Wang, Yunfeng Zhou   +2 more
semanticscholar   +1 more source

Development of a prognostic model for mortality in COVID-19 infection using machine learning

Modern Pathology, 2020
Coronavirus disease 2019 (COVID-19) is a novel disease resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has quickly risen since the beginning of 2020 to become a global pandemic. As a result of the rapid
Adam L. Booth, E. Abels, P. McCaffrey
semanticscholar   +1 more source

A prognostic model for colorectal cancer based on CEA and a 48-multiplex serum biomarker panel

Scientific Reports, 2021
Mortality in colorectal cancer (CRC) remains high, resulting in 860,000 deaths annually. Carcinoembryonic antigen is widely used in clinics for CRC patient follow-up, despite carrying a limited prognostic value.
Kajsa Björkman, S. Jalkanen, M. Salmi, H. Mustonen, Tuomas Kaprio, H. Kekki, K. Pettersson, C. Böckelman, C. Haglund   +8 more
semanticscholar   +1 more source

Promoting Prognostic Model Application: A Review Based on Gliomas

Journal of Oncology, 2021
Malignant neoplasms are characterized by poor therapeutic efficacy, high recurrence rate, and extensive metastasis, leading to short survival. Previous methods for grouping prognostic risks are based on anatomic, clinical, and pathological features that ...
Xisong Liang, Zeyu Wang, Ziyu Dai, Hao Zhang, Q. Cheng, Zhixiong Liu   +5 more
semanticscholar   +1 more source

Development and validation of a RNA binding protein-associated prognostic model for lung adenocarcinoma

Aging, 2020
RNA binding proteins (RBPs) dysregulation have been reported in various malignant tumors and associated with the occurrence and development of cancer. However, the role of RBPs in lung adenocarcinoma (LUAD) is poorly understood.
Wei Li, Lina Gao, Peipei Song, Chong-Ge You   +3 more
semanticscholar   +1 more source

Development and validation of a novel immune-related prognostic model in hepatocellular carcinoma

Journal of Translational Medicine, 2020
Growing evidence has suggested that immune-related genes play crucial roles in the development and progression of hepatocellular carcinoma (HCC). Nevertheless, the utility of immune-related genes for evaluating the prognosis of HCC patients are still ...
Z. Wang, Jie Zhu, Yongjuan Liu, Changhong Liu, Wenqi Wang, Feng-zhe Chen, Lixian Ma   +6 more
semanticscholar   +1 more source