Results 21 to 30 of about 866,709 (207)
A signature-based classification of lung adenocarcinoma that stratifies tumor immunity
Frontiers in Oncology, 2023 BackgroundImmune-related subgroup classification in immune checkpoint blockade (ICB) therapy is largely inconclusive in lung adenocarcinoma (LUAD).Materials and methodsFirst, the single-sample Gene Set Enrichment Analysis (ssGSEA) and K-means algorithms ...
Xun Zhang +5 more
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Frontiers in Cell and Developmental Biology, 2023 Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma which that highly aggressive and heterogeneous. Glycolysis has been implicated in the regulation of tumor microenvironment (TME) and development.
Yingying Cui +4 more
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HeliyonFollicular lymphoma (FL) is a common B-cell lymphoma and typically affects the elderly population. It is urgently required to enhance our comprehension of disease-specific outcomes in elderly FL patients and identify a reliable predictive indicator to ...
Jiesong Wang +13 more
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A Bayesian adaptive marker‐stratified design for molecularly targeted agents with customized hierarchical modeling [PDF]
, 2019 It is well known that the treatment effect of a molecularly targeted agent (MTA) may vary dramatically, depending on each patient's biomarker profile. Therefore, for a clinical trial evaluating MTA, it is more reasonable to evaluate its treatment effect ...
Cao, Sha +4 more
core +3 more sources
Scientific ReportsMultiple myeloma (MM) is a common hematological malignancy, and its prognostic factors have been extensively studied. Progression of disease within 24 months (POD24) suggests a poor prognosis in many malignancies, but is rarely mentioned in MM.
Yongqin Cao +5 more
doaj +1 more source
Frontiers in HematologyBackgroundDisease related anemia in myelofibrosis (MF) is common and prognostically detrimental. Anemia in MF poses a therapeutic challenge as it contributes to poor quality of life and often interferes with JAK inhibitor therapy.
Somedeb Ball +11 more
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Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease [PDF]
, 2014 © 2014 John Wiley & Sons Ltd. Defining the prognosis of individual cancer sufferers remains a significant clinical challenge. Here we assessed the ability of high-resolution single telomere length analysis (STELA), combined with an experimentally ...
Allan, James M. +14 more
core +1 more source
Establish immune-related gene prognostic index for esophageal cancer
Frontiers in Genetics, 2022 Background: Esophageal cancer is a tumor type with high invasiveness and low prognosis. As immunotherapy has been shown to improve the prognosis of esophageal cancer patients, we were interested in the establishment of an immune-associated gene ...
Caiyu Guo +6 more
doaj +1 more source
A Similarity-Based Prognostics Approach for Remaining Useful Life Prediction [PDF]
, 2014 Physics-based and data-driven models are the two major prognostic approaches in the literature with their own advantages and disadvantages. This paper presents a similarity-based data-driven prognostic methodology and efficiency analysis study on ...
Camci, Faith +2 more
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Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection [PDF]
, 2015 There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher ...
A Bhangu +31 more
core +2 more sources