Results 31 to 40 of about 854,600 (203)
A Bayesian adaptive marker‐stratified design for molecularly targeted agents with customized hierarchical modeling [PDF]
, 2019 It is well known that the treatment effect of a molecularly targeted agent (MTA) may vary dramatically, depending on each patient's biomarker profile. Therefore, for a clinical trial evaluating MTA, it is more reasonable to evaluate its treatment effect ...
Cao, Sha +4 more
core +3 more sources
Scientific ReportsMultiple myeloma (MM) is a common hematological malignancy, and its prognostic factors have been extensively studied. Progression of disease within 24 months (POD24) suggests a poor prognosis in many malignancies, but is rarely mentioned in MM.
Yongqin Cao +5 more
doaj +1 more source
Frontiers in HematologyBackgroundDisease related anemia in myelofibrosis (MF) is common and prognostically detrimental. Anemia in MF poses a therapeutic challenge as it contributes to poor quality of life and often interferes with JAK inhibitor therapy.
Somedeb Ball +11 more
doaj +1 more source
Operational Prognostic Model Evaluation
PHM Society Asia-Pacific Conference, 2023 Prognostic analytic models have become a viable way to reduce operational interruptions when sufficient timely data is available. This work describes a set of evaluation metrics which can characterize model performance as a degradation estimate and as a decision enabler.
Shashvat Prakash +2 more
openaire +1 more source
Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease [PDF]
, 2014 © 2014 John Wiley & Sons Ltd. Defining the prognosis of individual cancer sufferers remains a significant clinical challenge. Here we assessed the ability of high-resolution single telomere length analysis (STELA), combined with an experimentally ...
Allan, James M. +14 more
core +1 more source
Establish immune-related gene prognostic index for esophageal cancer
Frontiers in Genetics, 2022 Background: Esophageal cancer is a tumor type with high invasiveness and low prognosis. As immunotherapy has been shown to improve the prognosis of esophageal cancer patients, we were interested in the establishment of an immune-associated gene ...
Caiyu Guo +6 more
doaj +1 more source
A Similarity-Based Prognostics Approach for Remaining Useful Life Prediction [PDF]
, 2014 Physics-based and data-driven models are the two major prognostic approaches in the literature with their own advantages and disadvantages. This paper presents a similarity-based data-driven prognostic methodology and efficiency analysis study on ...
Camci, Faith +2 more
core +1 more source
Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection [PDF]
, 2015 There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher ...
A Bhangu +31 more
core +2 more sources
Frontiers in ImmunologyBackgroundCurrently, adequate treatment and prognostic prediction means for Hepatocellular Carcinoma (HCC) haven’t entered into medical vision. Tanshinone IIA (TanIIA) is a natural product, which can be utilized as a potential treatment of HCC due to its
Lichao Qian +8 more
doaj +1 more source
Construction of a solid Cox model for AML patients based on multiomics bioinformatic analysis
Frontiers in Oncology, 2022 Acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy. The bone marrow (BM) microenvironment in AML plays an important role in leukemogenesis, drug resistance and leukemia relapse.
Fu Li +7 more
doaj +1 more source