Results 121 to 130 of about 2,292,592 (309)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Naples Prognostic Score as a Novel Prognostic Prediction Tool for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma After Neoadjuvant Therapy [PDF]
Weiming Chen,1– 3,* Guobing Xu,1– 3,* Xin Yan,4,* Shuo Wang,1– 3 Qichang Xie,1– 3 Qing Liu,5 Bin Zheng,1– 3 Chun Chen,1– 3 Yong Zhu,1– 3 Zhang Yang1– 3 1Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian,
Yang Z +9 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
, 2018 Jingfeng Lu,1,* Yi Chen,1,* Yanxia Liu,2,* Junbin Ding,1 Zhenhao Piao,1 Weiyan Liu1 1Department of General Surgery, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People’s Republic of China; 2Department of Nursing, Minhang Hospital ...
Liu Y +5 more
core
Indian Spine JournalBackground: The modified Tokuhashi score (mTS) has been extensively used to predict survival in patients with spine metastasis (SM). Studies evaluating its applicability and accuracy differ, with some affirming its validity while others deem it obsolete.
Vijay Alagar +4 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis [PDF]
Background With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and biochemical ...
Granit, Volkan +14 more
core +1 more source
A Novel Prognostic Score Based on ZG16 for Predicting CRC Survival
Pharmacogenomics and Personalized Medicine, 2020 Wei Wang,1,2,* Jian-Fang Sun,3,* Xiao-Zhong Wang,1 Hou-Qun Ying,4 Xia-Hong You,1 Fan Sun1 1Jiangxi Province Key Laboratory of Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Nanchang 330006 ...
Wang W +5 more
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source