Results 51 to 60 of about 1,264,892 (364)

A novel prognostic 6-gene signature for osteoporosis

Frontiers in Endocrinology, 2022
IntroductionThe incidence of osteoporosis (OP) keeps increasing due to global aging of the population. Therefore, identifying the diagnostic and prognostic biomarkers of OP is of great significance.MethodsmRNA data from OP and non-OP samples were obtained from GEO database, which were divided into training set (GSE35959) and testing sets (GSE7158 ...
Yu Zhao, Yu Zhao, Jieping Yan, Jieping Yan, Yimiao Zhu, Zhenping Han, Tingting Li, Lijuan Wang   +7 more
openaire   +3 more sources

Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer

Frontiers in Oncology, 2022
BackgroundEnergy metabolism has been considered as one of the novel features of neoplasms. This study aimed to establish the prognostic signature for pancreatic cancer (PC) based on metabolism-related genes (MRGs).MethodsWe obtained MRGs from the ...
Hui Chen, Fuqiang Zu, Taofei Zeng, Ziang Chen, Jinhong Wei, Peng Liu, Zeyu Li, Lei Zhou, Huaitao Wang, Hao Tan, Xiaodong Tan   +10 more
doaj   +1 more source

Construction of a Prognostic Signature of 10 Autophagy-Related lncRNAs in Gastric Cancer

International Journal of General Medicine, 2022
Background Autophagy plays a double-edged sword role in cancers. LncRNAs could regulate cancer initiation and development at various levels. However, the role of autophagy-related lncRNAs (ARlncs) in gastric cancer (GC) remains indistinct.
Wenwen Wang, Q. Pei, Lifen Wang, T. Mu, H. Feng   +4 more
semanticscholar   +1 more source

Prognostic relevance of gene-expression signatures

, 2022
Cancer prognosis can be regarded as estimating the risk of future outcomes from multiple variables. In prognostic signatures, these variables represent expressions of genes that are summed up to calculate a risk score. However, it is a natural phenomenon in living systems that the whole is more than the sum of its parts.
Tschodu, Dimitrij, Lippoldt, Jürgen, Gottheil, Pablo, Wegscheider, Anne-Sophie, Niendorf, Axel, Käs, Josef A.   +5 more
openaire   +2 more sources

Six-lncRNA Immune Prognostic Signature for Cervical Cancer [PDF]

Frontiers in Genetics, 2020
This study searched for immune-related long noncoding RNAs (lncRNAs) to predict the prognosis of patients with cervical cancer.We obtained immunologically relevant lncRNA expression profiles and clinical follow-up data from cervical cancer patients from The Cancer Genome Atlas database and the Molecular Signatures Database.
Qian Chen, Lang Hu, Dongping Huang, Kaihua Chen, Xiaoqiang Qiu, Bingqing Qiu   +5 more
openaire   +3 more sources

Exploration of prognostic genes and risk signature in breast cancer patients based on RNA binding proteins associated with ferroptosis

Frontiers in Genetics, 2023
Background: Breast cancer (BRCA) is a life-threatening malignancy in women with an unsatisfactory prognosis. The purpose of this study was to explore the prognostic biomarkers and a risk signature based on ferroptosis-related RNA-binding proteins (FR ...
Xiang Chen, Changcheng Yang, Wei Wang, Xionghui He, Hening Sun, Wenzhi Lyu, Kejian Zou, Shuo Fang, Shuo Fang, Zhijun Dai, Huaying Dong   +10 more
doaj   +1 more source

Identification and validation of the molecular subtype and prognostic signature for clear cell renal cell carcinoma based on neutrophil extracellular traps

Frontiers in Cell and Developmental Biology, 2022
Background: Renal cell carcinoma (RCC) is one of the most common cancers, with an annual incidence of nearly 400,000 cases worldwide. Increasing evidence has also demonstrated the vital role of neutrophil extracellular traps (NETs) in cancer progression ...
Jing Quan, Banggao Huang
semanticscholar   +1 more source

Identification of LncRNA Prognostic Signature Associated With Genomic Instability in Pancreatic Adenocarcinoma

Frontiers in Oncology, 2022
Background Genomic instability (GI) is a critical feature of cancer which plays a key role in the occurrence and development of pancreatic adenocarcinoma (PAAD).
Jinfeng Zhu, Qian Huang, Xingyu Peng, Chen Luo, Sicheng Liu, Zitao Liu, Xun Wu, Hongliang Luo   +7 more
semanticscholar   +1 more source

An energy metabolism-based eight-gene signature correlates with the clinical outcome of esophagus carcinoma

BMC Cancer, 2021
Background The essence of energy metabolism has spread to the field of esophageal cancer (ESC) cells. Herein, we tried to develop a prognostic prediction model for patients with ESC based on the expression profiles of energy metabolism associated genes ...
Weifeng Zheng, Chaoying Chen, Jianghao Yu, Chengfeng Jin, Tiemei Han   +4 more
doaj   +1 more source

Construction of a prognostic signature for serous ovarian cancer based on lactate metabolism-related genes

Frontiers in Oncology, 2022
BackgroundThe key biochemical feature of malignant tumor is the conversion of energy metabolism from oxidative phosphorylation to glycolysis, which provides sufficient capacity and raw materials for tumor cell rapid growth.
Jiangdong Xiang, Rongjia Su, Sufang Wu, Lina Zhou   +3 more
doaj   +1 more source