Results 1 to 10 of about 7,104,659 (300)

Programmed Cell Death Tunes Tumor Immunity

Frontiers in Immunology, 2022
The demise of cells in various ways enables the body to clear unwanted cells. Studies over the years revealed distinctive molecular mechanisms and functional consequences of several key cell death pathways.
Jing Liu, Jing Liu, Minjing Hong, Yijia Li, Yijia Li, Dan Chen, Yangzhe Wu, Yi Hu   +7 more
doaj   +1 more source

Programmed cell death-1 and programmed cell death ligand-1 antibodies-induced dysthyroidism

Endocrine Connections, 2018
Background: Monoclonal antibodies blocking the programmed cell death-1 (PD-1) or its ligand (PD-L1) are a group of immune checkpoints inhibitors (ICIs) with proven antitumor efficacy.
Jaafar Jaafar, Eugenio Fernandez, Heba Alwan, Jacques Philippe   +3 more
doaj   +1 more source

Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas?

Haematologica, 2016
Therapeutic strategies targeting the programmed cell death-ligand 1/programmed cell death-1 pathway have shown significant responses and good tolerability in solid malignancies.
Fabienne McClanahan, Thomas G. Sharp, John G. Gribben   +2 more
doaj   +1 more source

Induction of Apoptotic Cell Death Leads to the Development of Bacterial Rot Caused by Pseudomonas cichorii

Molecular Plant-Microbe Interactions, 2006
Pseudomonas cichorii is the major causal agent of bacterial rot of lettuce. Collapse and browning symptoms were observed in lettuce leaf tissue from 15 to 24 h after inoculation (HAI) with P.cichorii; superoxide anion generation was detected at 1 to 6 ...
Akinori Kiba, Yasutaka Sangawa, Kouhei Ohnishi, Nan Yao, Pyoyun Park, Hitoshi Nakayashiki, Yukio Tosa, Shigeyuki Mayama, Yasufumi Hikichi   +8 more
doaj   +1 more source

Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism

Biology, 2023
The main purpose of this Special Issue is to provide readers with current understandings of the interactions and causal relations among injury stimuli (including microorganism infections), immune response and overnutrition/lipotoxicity in disease ...
Ligen Yu
doaj   +1 more source

Nitric Oxide and Reactive Oxygen Species Do Not Elicit Hypersensitive Cell Death but Induce Apoptosis in the Adjacent Cells During the Defense Response of Oat

Molecular Plant-Microbe Interactions, 2004
Nitric oxide (NO) acts as a signaling molecule in many cellular responses in plants and animals. Oat plants (Avena sativa L.) evoke the hypersensitive response (HR), which shares morphological and biochemical features with mammalian apoptosis, such as ...
Yasuomi Tada, Tomoyo Mori, Takeshi Shinogi, Nan Yao, Satsuki Takahashi, Shigeyuki Betsuyaku, Masaru Sakamoto, Pyoyun Park, Hitoshi Nakayashiki, Yukio Tosa, Shigeyuki Mayama   +10 more
doaj   +1 more source

Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]

PLoS ONE, 2013
Vertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Karl J Wahlin, Raymond A Enke, John A Fuller, Giedrius Kalesnykas, Donald J Zack, Shannath L Merbs   +5 more
doaj   +1 more source

Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity

Cells, 2022
Current research proves that immune dysregulation is a common feature of coronavirus disease 2019 (COVID-19), and immune exhaustion is associated with increased disease mortality.
Paulina Niedźwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, Izabela Korona-Głowniak, Jacek Roliński, Miłosz Parczewski   +8 more
doaj   +1 more source

Regulation of a Virus-Induced Lethal Disease in Tomato Revealed by LongSAGE Analysis

Molecular Plant-Microbe Interactions, 2007
Infection of Cucumber mosaic virus (CMV) and D satellite RNA (satRNA) in tomato plants induces rapid plant death, which has caused catastrophic crop losses.
Saeed Irian, Ping Xu, Xinbin Dai, Patrick X. Zhao, Marilyn J. Roossinck   +4 more
doaj   +1 more source

Transarterial Chemoembolization Combined With PD-1 Inhibitors Plus Lenvatinib Showed Improved Efficacy for Treatment of Unresectable Hepatocellular Carcinoma Compared With PD-1 Inhibitors Plus Lenvatinib

Technology in Cancer Research & Treatment, 2023
Background: Programmed cell death protein-1 inhibitors combined with lenvatinib have become a popular treatment option for patients with unresectable hepatocellular carcinoma.
Jinfeng Wang MM, Man Zhao MM, Guangjie Han MM, Xin Han MM, Jianfei Shi PhD, Lili Mi PhD, Ning Li BM, Xiaolei Yin MM, Xiaoling Duan PhD, Jiaojiao Hou MM, Fei Yin PhD   +10 more
doaj   +1 more source