Results 1 to 10 of about 1,245,864 (402)

Programmed Cell Death in Cystinosis [PDF]

Cells, 2022
Cystinosis is a lethal autosomal recessive disease that has been known clinically for over 100 years. There are now specific treatments including dialysis, renal transplantation and the orphan drug, cysteamine, which greatly improve the duration and ...
Elizabeth G. Ames, Jess G. Thoene
doaj   +3 more sources

Programmed Cell Death Tunes Tumor Immunity

Frontiers in Immunology, 2022
The demise of cells in various ways enables the body to clear unwanted cells. Studies over the years revealed distinctive molecular mechanisms and functional consequences of several key cell death pathways.
Jing Liu, Jing Liu, Minjing Hong, Yijia Li, Yijia Li, Dan Chen, Yangzhe Wu, Yi Hu   +7 more
doaj   +2 more sources

Programmed Cell Death in Cancer [PDF]

MedComm
Cancer remains the most lethal disease globally, despite the significant progress made in early screening, surgery, and therapeutic development in recent decades.
Yuang Wei, William Hankey, Dongliang Xu, Fuwen Yuan   +3 more
doaj   +2 more sources

Regulation of programmed cell death by Brd4

Cell Death and Disease, 2022
Epigenetic factor Brd4 has emerged as a key regulator of cancer cell proliferation. Targeted inhibition of Brd4 suppresses growth and induces apoptosis of various cancer cells.
Jinfeng Hu, Dun Pan, Guo Li, Kunqi Chen, Xiangming Hu   +4 more
doaj   +2 more sources

Programmed Cell Death in Rheumatoid Arthritis [PDF]

Journal of Inflammation Research
Luyuan Tong,* Jiao Qiu,* Yalin Xu, Shijing Lian, Yanqiu Xu, Xiao Wu The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, People’s Republic of China*These authors contributed equally to this ...
Tong L, Qiu J, Xu Y, Lian S, Xu Y, Wu X
doaj   +1 more source

Programmed Cell Death in Animal Development [PDF]

Cell, 1997
M. Jacobson, M. Weil, M. Raff
semanticscholar   +2 more sources

Programmed cell death [PDF]

WormBook, 2005
Programmed cell death is an integral component of C. elegans development. Genetic studies in C. elegans have led to the identification of more than two dozen genes that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells.
Barbara Conradt, Ding Xue
openaire   +5 more sources

Fungal-Induced Programmed Cell Death

Journal of Fungi, 2021
Fungal infections are a cause of morbidity in humans, and despite the availability of a range of antifungal treatments, the mortality rate remains unacceptably high.
Thomas J. Williams, Luis E. Gonzales-Huerta, Darius Armstrong-James   +2 more
doaj   +1 more source

Copper induces cell death by targeting lipoylated TCA cycle proteins

Science, 2022
Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. How excess copper induces cell death, however, is unknown.
Peter Tsvetkov, S. Coy, Boryana Petrova, Margaret B. Dreishpoon, A. Verma, M. Abdusamad, J. Rossen, Lena M Joesch-Cohen, Ranad Humeidi, R. Spangler, J. Eaton, Evgeni M. Frenkel, M. Kocak, S. M. Corsello, S. Lutsenko, Naama Kanarek, S. Santagata, T. Golub   +17 more
semanticscholar   +1 more source

Mitochondria-associated programmed cell death as a therapeutic target for age-related disease

Experimental and Molecular Medicine, 2023
Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production, support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate.
Thanh T Nguyen, Shibo Wei, Thu Ha Nguyen, Yunju Jo, Yan Zhang, Wonyoung Park, Karim Gariani, Chang-Myung Oh, Hyeon-ho Kim, Ki-Tae Ha, Kyu-Sang Park, Raekil Park, In-Kyu Lee, M. Shong, R. Houtkooper, D. Ryu   +15 more
semanticscholar   +1 more source