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NAC transcription factors ANAC087 and ANAC046 control distinct aspects of programmed cell death in the Arabidopsis columella and lateral root cap [PDF]

The Plant Cell, 2018
Programmed cell death in plants occurs both during stress responses and as an integral part of regular plant development. Despite the undisputed importance of developmentally controlled cell death processes for plant growth and reproduction, we are only ...
Andrade Buono, Rafael, Cubría Radío, Marta, De Winter, Freya, Fendrych, Matyas, Huysmans, Marlies, Karimi, Mansour, Mertens, Jan, Nowack, Moritz, Parizot, Boris, Skorzinski, Noemi   +9 more
core   +5 more sources

Programmed Cell Death Tunes Tumor Immunity

Frontiers in Immunology, 2022
The demise of cells in various ways enables the body to clear unwanted cells. Studies over the years revealed distinctive molecular mechanisms and functional consequences of several key cell death pathways.
Jing Liu, Jing Liu, Minjing Hong, Yijia Li, Yijia Li, Dan Chen, Yangzhe Wu, Yi Hu   +7 more
doaj   +2 more sources

Programmed cell death in hepatic fibrosis: current and perspectives

Cell Death Discovery, 2023
The initiation, development and resolution of hepatic fibrosis are influenced by various cytokines, chemokines, damage-associated molecular patterns (DAMPs) and signaling pathways.
Ju-Lu Lu, Chuan-Xin Yu, Li-Jun Song
doaj   +2 more sources

Programmed Cell Death in Cystinosis [PDF]

Cells, 2022
Cystinosis is a lethal autosomal recessive disease that has been known clinically for over 100 years. There are now specific treatments including dialysis, renal transplantation and the orphan drug, cysteamine, which greatly improve the duration and ...
Elizabeth G. Ames, Jess G. Thoene
doaj   +3 more sources

Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]

PLoS ONE, 2013
Vertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Karl J Wahlin, Raymond A Enke, John A Fuller, Giedrius Kalesnykas, Donald J Zack, Shannath L Merbs   +5 more
doaj   +6 more sources

Programmed Cell Death in Cancer [PDF]

MedComm
Cancer remains the most lethal disease globally, despite the significant progress made in early screening, surgery, and therapeutic development in recent decades.
Yuang Wei, William Hankey, Dongliang Xu, Fuwen Yuan   +3 more
doaj   +2 more sources

Regulation of programmed cell death by Brd4

Cell Death and Disease, 2022
Epigenetic factor Brd4 has emerged as a key regulator of cancer cell proliferation. Targeted inhibition of Brd4 suppresses growth and induces apoptosis of various cancer cells.
Jinfeng Hu, Dun Pan, Guo Li, Kunqi Chen, Xiangming Hu   +4 more
doaj   +2 more sources

Programmed cell death in triple-negative breast cancer [PDF]

Cellular & Molecular Biology Letters
Triple-negative breast cancer (TNBC) is a particularly aggressive and therapeutically challenging subtype of breast cancer, defined by the lack of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression.
Yaqi Liu, Jinwei He, Jialu Chen, Tianshun Chen, Wei Li, Zhihui Yang, Fancai Zeng   +6 more
doaj   +2 more sources

Programmed Cell Death in Rheumatoid Arthritis [PDF]

Journal of Inflammation Research
Luyuan Tong,* Jiao Qiu,* Yalin Xu, Shijing Lian, Yanqiu Xu, Xiao Wu The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, People’s Republic of China*These authors contributed equally to this ...
Tong L, Qiu J, Xu Y, Lian S, Xu Y, Wu X
doaj   +1 more source

Fungal-Induced Programmed Cell Death

Journal of Fungi, 2021
Fungal infections are a cause of morbidity in humans, and despite the availability of a range of antifungal treatments, the mortality rate remains unacceptably high.
Thomas J. Williams, Luis E. Gonzales-Huerta, Darius Armstrong-James   +2 more
doaj   +1 more source