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Programmed Cell Death in Cystinosis [PDF]
Cells, 2022 Cystinosis is a lethal autosomal recessive disease that has been known clinically for over 100 years. There are now specific treatments including dialysis, renal transplantation and the orphan drug, cysteamine, which greatly improve the duration and ...
Elizabeth G. Ames, Jess G. Thoene
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Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]
PLoS ONE, 2013 Vertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Karl J Wahlin +5 more
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Programmed Cell Death Tunes Tumor Immunity
Frontiers in Immunology, 2022 The demise of cells in various ways enables the body to clear unwanted cells. Studies over the years revealed distinctive molecular mechanisms and functional consequences of several key cell death pathways.
Jing Liu +7 more
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WormBook, 2005 Programmed cell death is an integral component of C. elegans development. Genetic studies in C. elegans have led to the identification of more than two dozen genes that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells.
Barbara Conradt, Ding Xue
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Fungal-Induced Programmed Cell Death
Journal of Fungi, 2021 Fungal infections are a cause of morbidity in humans, and despite the availability of a range of antifungal treatments, the mortality rate remains unacceptably high.
Thomas J. Williams +2 more
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Programmed cell death in cerebellar Purkinje neurons [PDF]
Journal of Integrative Neuroscience, 2022 Apoptosis, autophagy and necrosis are the three main types of programmed cell death. One or more of these types of programmed cell death may take place in neurons leading to their death in various neurodegenerative disorders in humans.
Nour S. Erekat
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Programmed cell death and liver diseases
Вестник трансплантологии и искусственных органов, 2022 Cell death represents the most critical pathologic entity in liver disease, which dictates pathologic consequences such as inflammation, fibrosis, and cell transformation.
N. A. Onishchenko +4 more
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Programmed Cell Death in Neurodevelopment [PDF]
Developmental Cell, 2015 Programmed cell death (PCD) is an evolutionarily conserved contributor to nervous system development. In the vertebrate peripheral nervous system, PCD is the basis of the neurotrophic theory, whereby cell death results from a surplus of neurons relative to target and competition for neurotrophic factors. In addition to stochastic cell death, PCD can be
Yoshifumi Yamaguchi +2 more
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Apoptosis, 2022 Research on cell death mechanisms gets a lot of attention. This is understandable as it underlies biology in general, as well as the insight in pathological conditions and the development of opportunities for therapeutic intervention. Over the last years a steady rise in the number of scientific reports and in the impact of this literature on the ...
Griffioen, Arjan W. +1 more
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Regulation of cell death in cancer - possible implications for immunotherapy [PDF]
, 2013 Since most anticancer therapies including immunotherapy trigger programmed cell death in cancer cells, defective cell death programs can lead to treatment resistance and tumor immune escape.
Fulda, Simone
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