Results 231 to 240 of about 1,266,471 (355)

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Epitranscriptomic modifications in programmed cell death: mechanistic insights and implications for liver diseases. [PDF]

Cell Mol Biol Lett
Chen L, Lu Y, Deng A, Cao J, Jin F, Huang H, Pan F, Liu Y, Li Y, Tong X, Yao H, Du J.   +11 more
europepmc   +1 more source

Prognostic risk modeling of endometrial cancer using programmed cell death-related genes: a comprehensive machine learning approach [PDF]

Tianshu Chen, Yuhan Yang, Zhizhong Huang, Feng Pan, Zaiyu Xiao, K. Gong, Wenguang Huang, Xu Liu, Xueqin Liu, Caiyun Fang   +9 more
openalex   +1 more source

3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants [PDF]

, 2015
Eumorphia G. Konstantakou, Gerassimos E. Voutsinas, Athanassios D. Velentzas, Aggeliki-Stefania Basogianni, Efthymios Paronis, Evangelos Balafas, Nikolaos Kostomitsopoulos, Konstantinos N. Syrigos, Ema Anastasiadou, Dimitrios J. Stravopodis   +9 more
openalex   +1 more source

Programmed Cell Death in Animal Development

Cell, 1997
M. Jacobson, M. Weil, M. Raff
semanticscholar   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Programmed Cell Death in Diabetic Kidney Disease: Mechanisms and Therapeutic Targeting. [PDF]

J Inflamm Res
Tang S, Sun Y, Sun W, Kang X, Zhao X, Jiang L, Gao Q, An X, Ji H, Lian F.   +9 more
europepmc   +1 more source

Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy

Jing Liu, Xiaomin Jiang, Youyou Li, Kaiting Yang, Ralph R. Weichselbaum, Wenbin Lin   +5 more
openalex   +2 more sources

Programmed Death Ligand 1 Indicates Pre-Existing Adaptive Immune Response by Tumor-Infiltrating CD8+ T Cells in Non-Small Cell Lung Cancer [PDF]

, 2019
Yiming Li, Jingmin Yu, Zhenyu Liu, Hai‐Jiao Yang, Juan Tang, Zhi‐Nan Chen   +5 more
openalex   +1 more source

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source