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Programmed Cell Death

Science, 1996
Letters from: [ Jan Novak ][1] [ Alice B. Fulton ][1] [ Jean Claude Ameisen ][1] Jean Claude Ameisen's Perspective “The origin of programmed cell death [PCD]” ([31 May, p. 1278][2]) discusses possible evolutionary roots of cell suicide.
openaire   +5 more sources

Programmed cell death in Drosophila

Neuron, 1994
Abstract During Drosophila development, large numbers of cells undergo natural cell death. Even though the onset of these deaths is controlled by many different signals, most of the dying cells undergo common morphological and biochemical changes that are characteristic of apoptosis in vertebrates. We have surveyed a large fraction of
H, Steller, M E, Grether
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Chlamydia and programmed cell death

Current Opinion in Microbiology, 2006
Discordant views regarding host cell death induction by Chlamydia are likely owing to the different methods used for evaluation of apoptosis. Apoptotic and non-apoptotic death owing to both caspase-dependent and -independent activation of the Bax protein occur late in the productive growth cycle. Evidence also suggests that Chlamydia inhibits apoptosis
Isao, Miyairi, Gerald I, Byrne
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Programmed cell death in Hydra

Seminars in Cancer Biology, 2007
Hydra is one of the simplest metazoans and thus an important model organism for studies on the evolution of developmental mechanisms in multi-cellular animals. In Hydra apoptosis is involved in the regulation of cell numbers in response to feeding, in regeneration and in the removal of non-self cells. It also participates in the maintenance of cellular
Angelika, Böttger, Olga, Alexandrova
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The biochemistry of programmed cell death

The FASEB Journal, 1995
Programmed cell death (PCD) is involved in the removal of superfluous and damaged cells in most organ systems. The induction phase of PCD or apoptosis is characterized by an extreme heterogeneity of potential PCD‐triggering signal transduction pathways.
Kroemer, Guido   +4 more
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Programmed cell death and cancer

Postgraduate Medical Journal, 2009
Abstract Programmed cell death (PCD) is an important terminal pathway for cells of multicellular organisms, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells.
Y, Sun, Z-L, Peng
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Programmed Cell Death in Development

1995
Although cell death has long been recognized to be a significant element in the process of embryonic morphogenesis, its relationships to differentiation and its mechanisms are only now becoming apparent. This new appreciation has come about not only through advances in the understanding of cell death in parallel immunological and pathological ...
E J, Sanders, M A, Wride
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Programmed cell death and radioresistance

Cancer and Metastasis Review, 1996
Whereas apoptosis is a critical mode of cell deletion in normal organism development, apoptotic cells are also observed in tumors, especially following cytotoxic treatments, leading to questions about their role in tumor response to therapy. We have conducted a series of studies using murine tumor models and found that the ability of the tumor cells to
R E, Meyn, L C, Stephens, L, Milas
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Programmed Cell Death in Prokaryotes

Critical Reviews in Microbiology, 1997
Programmed cell death (PCD), also referred to as apoptosis, is a cellular "suicide" mechanism, based on information from its own internal metabolism, environment, developmental history, and genome. This system was described in eukaryotes continuously along evolution, through amoebae, nematodes, insects, and animals.
Ayala Hochman
exaly   +3 more sources

Programmed cell death in the germline

Seminars in Cell & Developmental Biology, 2005
In many organisms, programmed cell death of germ cells is required for normal development. This often occurs through highly conserved events including the transfer of vital cellular material to the growing gametes following death of neighboring cells. Germline cell death also plays a role in such diverse processes as removal of abnormal or superfluous ...
J S, Baum, J P, St George, K, McCall
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