Results 21 to 30 of about 1,284,058 (379)

Insights into N6-methyladenosine and programmed cell death in cancer

open access: yesMolecular Cancer, 2022
N6-methyladenosine (m6A) methylation, the most common form of internal RNA modification in eukaryotes, has gained increasing attention and become a hot research topic in recent years.
L. Liu   +8 more
semanticscholar   +1 more source

Programmed cell death in spinal cord injury pathogenesis and therapy

open access: yesCell Proliferation, 2021
Spinal cord injury (SCI) always leads to functional deterioration due to a series of processes including cell death. In recent years, programmed cell death (PCD) is considered to be a critical process after SCI, and various forms of PCD were discovered ...
Zhongju Shi   +6 more
semanticscholar   +1 more source

Regulation of cell death in cancer - possible implications for immunotherapy [PDF]

open access: yes, 2013
Since most anticancer therapies including immunotherapy trigger programmed cell death in cancer cells, defective cell death programs can lead to treatment resistance and tumor immune escape.
Fulda, Simone
core   +2 more sources

Programmed cell death in atherosclerosis and vascular calcification

open access: yesCell Death and Disease, 2022
The concept of cell death has been expanded beyond apoptosis and necrosis to additional forms, including necroptosis, pyroptosis, autophagy, and ferroptosis.
Min Li   +5 more
semanticscholar   +1 more source

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

open access: yesJournal of Cell Biology, 1992
Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown ...
Yael Gavrieli   +2 more
semanticscholar   +1 more source

Programmed cell death-1 and programmed cell death ligand-1 antibodies-induced dysthyroidism

open access: yesEndocrine Connections, 2018
Background: Monoclonal antibodies blocking the programmed cell death-1 (PD-1) or its ligand (PD-L1) are a group of immune checkpoints inhibitors (ICIs) with proven antitumor efficacy.
Jaafar Jaafar   +3 more
doaj   +1 more source

Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism

open access: yesBiology, 2023
The main purpose of this Special Issue is to provide readers with current understandings of the interactions and causal relations among injury stimuli (including microorganism infections), immune response and overnutrition/lipotoxicity in disease ...
Ligen Yu
doaj   +1 more source

Reversal of an immunity associated plant cell death program by the growth regulator auxin [PDF]

open access: yes, 2007
One form of plant immunity against pathogens involves a rapid host programmed cell death at the site of infection accompanied by resistance, termed the hypersensitive response (HR).
Suresh Gopalan
core   +4 more sources

Progress in understanding the role of lncRNA in programmed cell death

open access: yesCell Death Discovery, 2021
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as chromatin, transcription, and post-transcription.
N. Jiang   +4 more
semanticscholar   +1 more source

Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas?

open access: yesHaematologica, 2016
Therapeutic strategies targeting the programmed cell death-ligand 1/programmed cell death-1 pathway have shown significant responses and good tolerability in solid malignancies.
Fabienne McClanahan   +2 more
doaj   +1 more source

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