Results 21 to 30 of about 1,245,864 (402)
Programmed Cell Death in Neurodevelopment [PDF]
Developmental Cell, 2015 Programmed cell death (PCD) is an evolutionarily conserved contributor to nervous system development. In the vertebrate peripheral nervous system, PCD is the basis of the neurotrophic theory, whereby cell death results from a surplus of neurons relative to target and competition for neurotrophic factors. In addition to stochastic cell death, PCD can be
Yoshifumi Yamaguchi +2 more
openaire +3 more sources
Programmed cell death in spinal cord injury pathogenesis and therapy
Cell Proliferation, 2021 Spinal cord injury (SCI) always leads to functional deterioration due to a series of processes including cell death. In recent years, programmed cell death (PCD) is considered to be a critical process after SCI, and various forms of PCD were discovered ...
Zhongju Shi +6 more
semanticscholar +1 more source
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
Journal of Cell Biology, 1992 Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown ...
Yael Gavrieli +2 more
semanticscholar +1 more source
Progress in understanding the role of lncRNA in programmed cell death
Cell Death Discovery, 2021 Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as chromatin, transcription, and post-transcription.
N. Jiang +4 more
semanticscholar +1 more source
Reversal of an immunity associated plant cell death program by the growth regulator auxin [PDF]
, 2007 One form of plant immunity against pathogens involves a rapid host programmed cell death at the site of infection accompanied by resistance, termed the hypersensitive response (HR).
Suresh Gopalan
core +4 more sources
Programmed cell death-1 and programmed cell death ligand-1 antibodies-induced dysthyroidism
Endocrine Connections, 2018 Background: Monoclonal antibodies blocking the programmed cell death-1 (PD-1) or its ligand (PD-L1) are a group of immune checkpoints inhibitors (ICIs) with proven antitumor efficacy.
Jaafar Jaafar +3 more
doaj +1 more source
Cells, 2022 Current research proves that immune dysregulation is a common feature of coronavirus disease 2019 (COVID-19), and immune exhaustion is associated with increased disease mortality.
Paulina Niedźwiedzka-Rystwej +8 more
doaj +1 more source
Regulation of cell death in cancer - possible implications for immunotherapy [PDF]
, 2013 Since most anticancer therapies including immunotherapy trigger programmed cell death in cancer cells, defective cell death programs can lead to treatment resistance and tumor immune escape.
Fulda, Simone
core +2 more sources
Haematologica, 2016 Therapeutic strategies targeting the programmed cell death-ligand 1/programmed cell death-1 pathway have shown significant responses and good tolerability in solid malignancies.
Fabienne McClanahan +2 more
doaj +1 more source
Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism
Biology, 2023 The main purpose of this Special Issue is to provide readers with current understandings of the interactions and causal relations among injury stimuli (including microorganism infections), immune response and overnutrition/lipotoxicity in disease ...
Ligen Yu
doaj +1 more source