Results 21 to 30 of about 1,266,471 (355)

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

Journal of Cell Biology, 1992
Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown ...
Yael Gavrieli, Y. Sherman, S. Ben‐Sasson   +2 more
semanticscholar   +1 more source

Programmed cell death-1 and programmed cell death ligand-1 antibodies-induced dysthyroidism

Endocrine Connections, 2018
Background: Monoclonal antibodies blocking the programmed cell death-1 (PD-1) or its ligand (PD-L1) are a group of immune checkpoints inhibitors (ICIs) with proven antitumor efficacy.
Jaafar Jaafar, Eugenio Fernandez, Heba Alwan, Jacques Philippe   +3 more
doaj   +1 more source

Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity

Cells, 2022
Current research proves that immune dysregulation is a common feature of coronavirus disease 2019 (COVID-19), and immune exhaustion is associated with increased disease mortality.
Paulina Niedźwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, Izabela Korona-Głowniak, Jacek Roliński, Miłosz Parczewski   +8 more
doaj   +1 more source

Reversal of an immunity associated plant cell death program by the growth regulator auxin [PDF]

, 2007
One form of plant immunity against pathogens involves a rapid host programmed cell death at the site of infection accompanied by resistance, termed the hypersensitive response (HR).
Suresh Gopalan
core   +4 more sources

Programmed cell death in spinal cord injury pathogenesis and therapy

Cell Proliferation, 2021
Spinal cord injury (SCI) always leads to functional deterioration due to a series of processes including cell death. In recent years, programmed cell death (PCD) is considered to be a critical process after SCI, and various forms of PCD were discovered ...
Zhongju Shi, Shiyang Yuan, Linlin Shi, Jia-he Li, G. Ning, Xiaohong Kong, S. Feng   +6 more
semanticscholar   +1 more source

Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas?

Haematologica, 2016
Therapeutic strategies targeting the programmed cell death-ligand 1/programmed cell death-1 pathway have shown significant responses and good tolerability in solid malignancies.
Fabienne McClanahan, Thomas G. Sharp, John G. Gribben   +2 more
doaj   +1 more source

Progress in understanding the role of lncRNA in programmed cell death

Cell Death Discovery, 2021
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as chromatin, transcription, and post-transcription.
N. Jiang, Xiaoyu Zhang, Xuejun Gu, Xiaozhuang Li, L. Shang   +4 more
semanticscholar   +1 more source

Transarterial Chemoembolization Combined With PD-1 Inhibitors Plus Lenvatinib Showed Improved Efficacy for Treatment of Unresectable Hepatocellular Carcinoma Compared With PD-1 Inhibitors Plus Lenvatinib

Technology in Cancer Research & Treatment, 2023
Background: Programmed cell death protein-1 inhibitors combined with lenvatinib have become a popular treatment option for patients with unresectable hepatocellular carcinoma.
Jinfeng Wang MM, Man Zhao MM, Guangjie Han MM, Xin Han MM, Jianfei Shi PhD, Lili Mi PhD, Ning Li BM, Xiaolei Yin MM, Xiaoling Duan PhD, Jiaojiao Hou MM, Fei Yin PhD   +10 more
doaj   +1 more source

Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism

Biology, 2023
The main purpose of this Special Issue is to provide readers with current understandings of the interactions and causal relations among injury stimuli (including microorganism infections), immune response and overnutrition/lipotoxicity in disease ...
Ligen Yu
doaj   +1 more source

Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure [PDF]

, 2010
Programmed cell elimination is an important pathological mediator of disease. Multiple pathways to programmed cell death have been delineated, including apoptosis, autophagy and programmed necrosis.
Dorn, Gerald W, II
core   +3 more sources