Results 241 to 250 of about 290,432 (308)

Intratumoral PD-1-directed IL-2 expression via oncolytic vaccinia virus elicits superior antitumor effects with enhanced safety. [PDF]

J Immunother Cancer
Chen L, Ye J, Patel S, Ming P, Li C, Waltermire J, Zhao J, Ren J, Bartlett DL, Liu Z.   +9 more
europepmc   +1 more source

A Reproducible and Scalable Process for High Yield Mesenchymal Stromal Cell Extracellular Vesicles Production

Advanced Materials Technologies, EarlyView.
Mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) are a promising therapeutic tool for regenerative medicine. However, the field lacks a reproducible high‐yield production method to answer the quantities needed for clinical translation.
Christophe Wong, Elise Madec, Jeanne Volatron, Max Piffoux, Amanda K. A. Silva, Florence Gazeau, Jean‐Philippe Herbeuval, Thibaut Fourniols   +7 more
wiley   +1 more source

Yifei Sanjie Formula in improving the response to PD-1 blockade by lung cancer through the attenuation of the USP7-NR1H4-bile acid metabolism axis. [PDF]

J Thorac Dis
Ren Y, Li Y, Fang C, Chen Z, Xiao Z.
europepmc   +1 more source

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

Advanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey, Harry Akligoh, Michael Finocchiaro, Abhishek Srihari Rampelli, Zongwei Wang, Aria F. Olumi, Tania Konry   +6 more
wiley   +1 more source

Immunotherapy in triple-negative breast cancer: mechanisms of resistance and emerging approaches: a narrative review. [PDF]

J Yeungnam Med Sci
Koh SA.
europepmc   +1 more source

Role and mechanism of gut microbiota in regulating interferon-mediated programmed cell death in colorectal cancer. [PDF]

Front Immunol
Yao Q, Chen S, Qian W, Yang C, Li J.
europepmc   +1 more source

Targeting NLRP3 inflammasome: a novel strategy for improving immune checkpoint inhibitor-associated pneumonitis. [PDF]

Transl Lung Cancer Res
Xiao SY, Ji YM, Liu Y, Lv YH, Dong Y, Liu MC, Lu YH, Cui PF, Li T, Cui XR, Hu Y.   +10 more
europepmc   +1 more source

Targeted inhibition of Nrf2 potentiates antitumor immunity and enhances the efficacy of immunotherapy in hepatocellular carcinoma. [PDF]

J Immunother Cancer
Zhu Y, Liu M, Fan X, Xu Y, Diao X, Bi J, Wan X, Assaraf YG, Kwok HF, Chen L.   +9 more
europepmc   +1 more source

The palmitoylation code in cell death signaling: from molecular mechanisms to therapeutic opportunities. [PDF]

Front Cell Dev Biol
Xiao HX, Li ZZ, Li XH, Chen T, Tang XR, Zhang Y, Wang ZX, Pan YP.   +7 more
europepmc   +1 more source

The role of ferroptosis in vascular endothelial cells and its role in the pathogenesis of cervical spondylosis of vertebral artery type: a comprehensive review. [PDF]

Braz J Med Biol Res
Fan X, Xu S, Gao H.
europepmc   +1 more source