Results 191 to 200 of about 2,386,530 (346)

Incidence of Pneumonitis With Use of Programmed Death 1 and Programmed Death‐Ligand 1 Inhibitors in Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Trials

Chest, 2017
Monica Khunger, S. Rakshit, V. Pasupuleti, Adrian V. Hernández, P. Mazzone, J. Stevenson, N. Pennell, V. Velcheti   +7 more
semanticscholar   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

644 Ocular adverse events associated with programmed death-1 and programmed death ligand-1 immunotherapy

Journal for ImmunoTherapy of Cancer, 2020
James Murray, Howard Streicher, Elad Sharon, Helen Chen, LeAnne Young, Shanda Finnigan, H Nida Sen   +6 more
doaj   +1 more source

Vogt-Koyanagi-Harada-like uveitis with severe hyalitis during treatment by anti-programmed death 1 antibody for lung cancer: a case report. [PDF]

J Med Case Rep
Liu X, Lu Y, Lu P, Zhang Y, Xia W.
europepmc   +1 more source

Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma.

Journal of Clinical Oncology, 2018
M. Roemer, R. Redd, F. Cader, Christine J. Pak, Sara Abdelrahman, Ouyang Jing, S. Sasse, A. Younes, M. Fanale, A. Santoro, P. Zinzani, J. Timmerman, G. Collins, R. Ramchandren, Jonathon B. Cohen, J. D. de Boer, J. Kuruvilla, K. Savage, M. Trněný, S. Ansell, Kazunobu Kato, B. Farsaci, A. Sumbul, P. Armand, D. Neuberg, G. Pinkus, A. Ligon, S. Rodig, M. Shipp   +28 more
semanticscholar   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Peripheral blood T lymphocytes are downregulated by the PD-1/PD-L1 axis in advanced gastric cancer

Archives of Medical Science, 2018
Witold Zgodzinski, Ewelina Grywalska, Krzysztof Zinkiewicz, Agata Surdacka, Marek Majewski, Artur Zakoscielny, Pawel Bury, Jacek Rolinski, Grzegorz T. Wallner   +8 more
doaj   +1 more source

Preliminary exploration of programmed death 1 inhibitor combined with fruquintinib and docetaxel for advanced colorectal cancer. [PDF]

World J Gastrointest Oncol
Meng XY, Cai YM, Sun NN, Zhang WH, Cui RX, Zhang L, Zheng CC, Sun Z, Luo WX, Wang FW.   +9 more
europepmc   +1 more source

Safety and Antitumor Activity of the Anti-Programmed Death-1 Antibody Pembrolizumab in Patients With Advanced Esophageal Carcinoma.

Journal of Clinical Oncology, 2018
T. Doi, S. Piha-Paul, S. Jalal, S. Saraf, J. Lunceford, M. Koshiji, J. Bennouna   +6 more
semanticscholar   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source