Results 51 to 60 of about 8,657,643 (253)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Extracting typing game keystroke patterns as potential indicators of programming aptitude

open access: yesFrontiers in Computer Science
This study attempted to determine whether individuals possess programming aptitude solely based on keystroke information from typing games where participants type computer programs.
Toyohisa Nakada, Motoki Miura
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The translator of Petri-object model visual programming language

open access: yes, 2022
High-level programming tools are aimed at increasing the development speed of complex programs due to automation within the routine actions of the programmer, reducing the number of coding errors and reducing the code in general.
Dyfuchyn, А.Yu.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Programming in Technology Teacher Education

open access: yes, 2022
More research on teaching technology alongside programming is needed. Many Swedish teachers feel uncertain about what the new content in the National curriculum for technology imply.
Perez, Anna
core   +3 more sources

Influence of Gamification on the Commitment of the Students of a Programming Course: A Case Study

open access: yesApplied Sciences
In the realm of programming education, enhancing student commitment is pivotal for both academic success and practical application. Traditional methodologies often fall short in catering to the evolving needs of today’s learners.
Francisco Calles-Esteban   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Fine-Tuning Generative AI with Domain Question Banks: Evaluating Multi-Type Question Generation and Grading

open access: yesApplied Sciences
This study examines the effectiveness of a fine-tuned generative AI system—trained with a domain question bank—for question generation and automated grading in programming education, and evaluates its instructional usability.
Chien-Hung Lai   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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